# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5168381 | A | Volume of distribution at steady state in BALB/c mouse at 5 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
2. | ALA5168382 | F | Cytotoxicity against mouse EMT6 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
3. | ALA5168383 | F | Cytotoxicity against mouse 3LL cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay | Mus musculus | 5 | cell-based format | Scientific Literature | ||
4. | ALA5168385 | A | Volume of distribution at steady state in BALB/c mouse at 1 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Mus musculus | 2 | organism-based format | Scientific Literature | ||
5. | ALA5168386 | A | Inhibition of CYP2C9 (unknown origin) at 20 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA5168387 | F | Antagonist activity at human EP4 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assay | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
7. | ALA5168388 | F | Antagonist activity at mouse EP4 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assay | Mus musculus | 10 | cell-based format | Scientific Literature | ||
8. | ALA5168389 | F | Antagonist activity at human EP1 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
9. | ALA5168390 | F | Antagonist activity at human EP2 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
10. | ALA5168391 | F | Antagonist activity at human EP3 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
11. | ALA5168392 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 7 | microsome format | Scientific Literature | ||
12. | ALA5168393 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 7 | microsome format | Scientific Literature | ||
13. | ALA5168394 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 10 uM measured after 60 mins | Homo sapiens | 7 | microsome format | Scientific Literature | ||
14. | ALA5168395 | A | Metabolic stability in mouse liver microsomes assessed as half life | Mus musculus | 7 | microsome format | Scientific Literature | ||
15. | ALA5168396 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 7 | microsome format | Scientific Literature | ||
16. | ALA5168397 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 10 uM measured after 60 mins | Mus musculus | 7 | microsome format | Scientific Literature | ||
17. | ALA5168398 | A | Inhibition of CYP1A2 (unknown origin) at 20 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
18. | ALA5168399 | A | Inhibition of CYP2B6 (unknown origin) at 20 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
19. | ALA5168400 | A | Inhibition of CYP2D6 (unknown origin) at 20 uM | Homo sapiens | 5 | single protein format | Scientific Literature | ||
20. | ALA5168401 | A | Inhibition of CYP2E1 (unknown origin) at 20 uM | Homo sapiens | 5 | single protein format | Scientific Literature |