# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5115594 | F | Antiproliferative activity against human HN-6 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay | Homo sapiens | 37 | ALA5113404 | cell-based format | Scientific Literature | |
2. | ALA5115595 | F | Antiproliferative activity against human CAL-27 cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay | Homo sapiens | 11 | ALA5113404 | cell-based format | Scientific Literature | |
3. | ALA5115596 | F | Antiproliferative activity against human FaDu cells assessed as cell growth inhibition incubated for 72 hrs by CCK-8 assay | Homo sapiens | 11 | ALA5113404 | cell-based format | Scientific Literature | |
4. | ALA5115597 | B | Inhibition of tubulin polymerization (unknown origin) at 20 micromol/L by fluorescence based analysis | Homo sapiens | 34 | ALA5113404 | protein complex format | Scientific Literature | |
5. | ALA5115598 | B | Inhibition of tubulin polymerization (unknown origin) by fluorescence based analysis | Homo sapiens | 13 | ALA5113404 | protein complex format | Scientific Literature | |
6. | ALA5115599 | F | Induction of cell morphological changes in human HN-6 cells assessed as decrease in tubulin network around nucleus at 100 nmol/L incubated for 24 hrs by DAPI staining based confocal microscopy analysis | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
7. | ALA5115600 | F | Antimigratory activity in human HN-6 cells assessed as inhibition of cell migration at 0.1 micromol/L measured after 24 hrs by scratch wound assay based fluorescence microscope analysis | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
8. | ALA5115601 | F | Inhibition of cell invasion in human HN-6 cells at 200 to 500 nmol/L incubated for 24 hrs by crystal violet staining based transwell assay | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
9. | ALA5115602 | F | Induction of apoptosis in human HN-6 cells assessed as viable cells at 0.1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 97.26%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
10. | ALA5115603 | F | Induction of apoptosis in human HN-6 cells assessed as early apoptotic cells at 0.1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 2.04%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
11. | ALA5115604 | F | Induction of apoptosis in human HN-6 cells assessed as late apoptotic cells at 0.1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 8.81%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
12. | ALA5115605 | F | Induction of apoptosis in human HN-6 cells assessed as necrotic cells at 0.1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 2.08%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
13. | ALA5115606 | F | Induction of apoptosis in human HN-6 cells assessed as viable cells at 1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 97.26%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
14. | ALA5115607 | F | Induction of apoptosis in human HN-6 cells assessed as early apoptotic cells at 1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 2.04%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
15. | ALA5115608 | F | Induction of apoptosis in human HN-6 cells assessed as late apoptotic cells at 1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 8.81%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
16. | ALA5115609 | F | Induction of apoptosis in human HN-6 cells assessed as necrotic cells at 1 micromol/L incubated for 24 hrs by Annexin-V/FITC-PI staining based flow cytometry analysis (Rvb = 2.08%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
17. | ALA5115610 | F | Induction of cell cycle arrest in human HN-6 cells assessed as accumulation of cells at G1 phase at 0.1 micromol/L incubated for 24 hrs by PI staining based flow cytometry analysi (Rvb = 45.33%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
18. | ALA5115611 | F | Induction of cell cycle arrest in human HN-6 cells assessed as accumulation of cells at S phase at 0.1 micromol/L incubated for 24 hrs by PI staining based flow cytometry analysi (Rvb = 32.12%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
19. | ALA5115612 | F | Induction of cell cycle arrest in human HN-6 cells assessed as accumulation of cells at S phase at 0.1 micromol/L incubated for 24 hrs by PI staining based flow cytometry analysi (Rvb = 31.19%) | Homo sapiens | 3 | ALA5113404 | cell-based format | Scientific Literature | |
20. | ALA5115613 | F | Antitumor activity against human HN-6 cells xenografted in mouse assessed as reduction on tumor growth at 80 mg/kg,IG administered daily for 2 weeks | Homo sapiens | 2 | ALA5113404 | organism-based format | Scientific Literature |