# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5098262 | F | Antiproliferative activity against ALK-positive human NCI-H3122 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
2. | ALA5098263 | F | Antiproliferative activity against ALK-positive human KARPAS-299 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
3. | ALA5098265 | B | Protac activity at CRBN/EML4-ALK in human NCI-H3122 cells assessed as induction of EML4-ALK fusion protein degradation at 1 uM incubated for 16 hrs by Western blot analysis relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
4. | ALA5098266 | B | Protac activity at CRBN/EML4-ALK in human NCI-H3122 cells assessed as induction of EML4-ALK fusion protein degradation at 0.1 uM incubated for 16 hrs by Western blot analysis relative to control | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
5. | ALA5098271 | B | Protac activity at CRBN/NPM-ALK in human KARPAS-299 cells assessed as induction of NPM-ALK fusion protein degradation at 1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
6. | ALA5098272 | B | Protac activity at CRBN/NPM-ALK in human KARPAS-299 cells assessed as induction of NPM-ALK fusion protein degradation at 0.1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature |