| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5167480 | B | Displacement of [125I]R3/I5 from human RXFP3 expressed in CHO-K1 cells membrane assessed as inhibition constant incubated for 1 hr by microplate scintillation counting analysis | Homo sapiens | 3 | ALA5154921 | cell membrane format | Scientific Literature | |
| 2. | ALA5167481 | F | Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation measured after 30 mins in presence of relaxin-3 by TR-FRET assay | Homo sapiens | 31 | ALA5154921 | cell-based format | Scientific Literature | |
| 3. | ALA5167494 | F | Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as [35S]GTPgammaS binding incubated for 1 hr by [35S]GTP-gammaS binding assay | Homo sapiens | 3 | ALA5154921 | cell-based format | Scientific Literature | |
| 4. | ALA5167497 | F | Antagonist activity at human RXFP3 expressed in CHO-K1 cells assessed as inhibition of relaxin-3 stimulated ERK1/2 phosphorylation preincubated for 15 mins followed by relaxin-3 addition for 5 mins | Homo sapiens | 3 | ALA5154921 | cell-based format | Scientific Literature | |
| 5. | ALA5167499 | F | Antagonist activity at human RXFP1 receptor expressed in CHO-K1 cells assessed as cAMP production at 10 to 30 uM in presence of relaxin-3 incubated for 30 mins by TR-FRET assay | Homo sapiens | 1 | ALA5154921 | cell-based format | Scientific Literature |
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