# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5118401 | F | Cell cycle arrest in human Bel-7402 cells assessed as accumulation at S phase at 1 uM measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 31%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
2. | ALA5118402 | F | Cell cycle arrest in human Bel-7402 cells assessed as accumulation at G1 phase at 1 uM measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 38.72%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
3. | ALA5118403 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at G2/M phase at 0.4 uM measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 19.93%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
4. | ALA5118404 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at S phase at 0.4 uM measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 32.81%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
5. | ALA5118405 | F | Cell cycle arrest in human HepG2 cells assessed as accumulation at G1 phase at 0.4 uM measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 42.27%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
6. | ALA5118406 | F | Induction of apoptosis in human HepG2 cells assessed as necrotic cells cells at 0.2 uM measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 2.04%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
7. | ALA5118407 | F | Induction of apoptosis in human HepG2 cells assessed as late apoptotic cells cells at 0.2 uM measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.66%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
8. | ALA5118408 | F | Induction of apoptosis in human HepG2 cells assessed as early apoptotic cells cells at 0.2 uM measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 1.81%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
9. | ALA5118409 | F | Induction of apoptosis in human HepG2 cells assessed as viable cells at 0.2 uM measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 94.5%) | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
10. | ALA5118410 | F | Induction of apoptosis in human HepG2 cells measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
11. | ALA5118411 | F | Induction of apoptosis in human HepG2 cells assessed as chromatin shrinkage at 0.2 to 0.8 uM measured after 48 hrs by Hoechst 33342 staining based fluorescence microscopy | Homo sapiens | 1 | ALA5113500 | cell-based format | Scientific Literature | |
12. | ALA5118412 | F | Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition at 1 uM measured after 72 hrs by MTT assay relative to control | Homo sapiens | 39 | ALA5113500 | cell-based format | Scientific Literature | |
13. | ALA5118413 | F | Antiproliferative activity against human HepG2 cells measured after 72 hrs by MTT assay | Homo sapiens | 24 | ALA5113500 | cell-based format | Scientific Literature | |
14. | ALA5118414 | F | Antiproliferative activity against human Bel-7402 cells measured after 72 hrs by MTT assay | Homo sapiens | 24 | ALA5113500 | cell-based format | Scientific Literature | |
15. | ALA5118415 | F | Antiproliferative activity against human HeLa cells measured after 72 hrs by MTT assay | Homo sapiens | 24 | ALA5113500 | cell-based format | Scientific Literature | |
16. | ALA5118416 | F | Antiproliferative activity against human Eca-109 cells measured after 72 hrs by MTT assay | Homo sapiens | 24 | ALA5113500 | cell-based format | Scientific Literature | |
17. | ALA5118417 | F | Antiproliferative activity against human PANC-1 cells measured after 72 hrs by MTT assay | Homo sapiens | 24 | ALA5113500 | cell-based format | Scientific Literature | |
18. | ALA5118418 | T | Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay | Homo sapiens | 2 | ALA5113500 | cell-based format | Scientific Literature | |
19. | ALA5118419 | T | Selectivity index, ratio of IC50 for human L02 cells to IC50 for human HepG2 cells | Homo sapiens | 2 | ALA5113500 | assay format | Scientific Literature | |
20. | ALA5118420 | P | Solubility of the compound in 5% DMSO and 10% Solutol HS-15 saline solution | 2 | ALA5113500 | small-molecule physicochemical format | Scientific Literature |