| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5133209 | F | Inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentration by calcium mobilization assay | Homo sapiens | 16 | ALA5131409 | cell-based format | Scientific Literature | |
| 2. | ALA5133210 | F | Antagonist activity at human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as minimal acetylcholine response by calcium mobilization assay relative to control | Homo sapiens | 14 | ALA5131409 | cell-based format | Scientific Literature | |
| 3. | ALA5133213 | F | Inhibition of human muscarinic acetylcholine M2 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentration by calcium mobilization assay | Homo sapiens | 7 | ALA5131409 | cell-based format | Scientific Literature | |
| 4. | ALA5133214 | B | Selectivity ratio of IC50 for inhibition of human muscarinic acetylcholine M2 receptor to IC50 for inhibition of human muscarinic acetylcholine M4 receptor expressed in CHO cells co-expressing Gqi5 in the presence of acetylcholine at EC80 concentration by calcium mobilization assay | 7 | ALA5131409 | cell-based format | Scientific Literature | ||
| 5. | ALA5133215 | A | Inhibition of CYP1A2 in human liver microsomes using cocktail of isoform-specific probe substrate | Homo sapiens | 7 | ALA5131409 | microsome format | Scientific Literature | |
| 6. | ALA5133216 | A | Inhibition of CYP2C9 in human liver microsomes using cocktail of isoform-specific probe substrate | Homo sapiens | 7 | ALA5131409 | microsome format | Scientific Literature | |
| 7. | ALA5133217 | A | Inhibition of CYP2D6 in human liver microsomes using cocktail of isoform-specific probe substrate | Homo sapiens | 7 | ALA5131409 | microsome format | Scientific Literature | |
| 8. | ALA5133218 | A | Inhibition of CYP3A4 in human liver microsomes using cocktail of isoform-specific probe substrate | Homo sapiens | 7 | ALA5131409 | microsome format | Scientific Literature | |
| 9. | ALA5133219 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 7 | ALA5131409 | microsome format | Scientific Literature | |
| 10. | ALA5133220 | A | Intrinsic clearance in rat liver microsomes | Rattus norvegicus | 1 | ALA5131409 | microsome format | Scientific Literature | |
| 11. | ALA5133222 | A | Plasma clearance in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 12. | ALA5133223 | A | Volume of distribution in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 13. | ALA5133224 | A | Elimination half life in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 14. | ALA5133225 | A | MRT in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 15. | ALA5133226 | A | AUC (0 to last) in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 16. | ALA5133227 | A | AUC (0 to infinity) in rat at 3 mg/kg, iv | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 17. | ALA5133228 | A | Cmax in rat plasma at 3 mg/kg, ip | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 18. | ALA5133229 | A | Cmax in mouse plasma at 3 mg/kg, ip | Mus musculus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 19. | ALA5133230 | A | Unbound Cmax in rat plasma at 3 mg/kg, ip | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature | |
| 20. | ALA5133231 | A | Cmax in rat brain at 3 mg/kg, ip | Rattus norvegicus | 1 | ALA5131409 | organism-based format | Scientific Literature |
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