# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5165265 | Binding | Inhibition of SPHK2 (unknown origin) using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assay | Homo sapiens | 12 | ALA5154877 | single protein format | Scientific Literature | |
2. | ALA5165266 | Binding | Inhibition of SPHK1 (unknown origin) at 10 uM using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assay relative to control | Homo sapiens | 26 | ALA5154877 | single protein format | Scientific Literature | |
3. | ALA5165267 | Binding | Inhibition of SPHK1 (unknown origin) using sphingosine-fluorescein as substrate incubated for 1 hr in presence of ATP by mobility shift assay | Homo sapiens | 12 | ALA5154877 | single protein format | Scientific Literature | |
4. | ALA5165320 | ADME | Tmax in mouse at 20 mg/kg, po | Mus musculus | 2 | ALA5154877 | organism-based format | Scientific Literature | |
5. | ALA5165323 | ADME | Cmax in mouse at 20 mg/kg, po | Mus musculus | 2 | ALA5154877 | organism-based format | Scientific Literature | |
6. | ALA5165326 | ADME | AUClast in mouse at 20 mg/kg, po | Mus musculus | 2 | ALA5154877 | organism-based format | Scientific Literature | |
7. | ALA5165327 | ADME | AUClast in mouse at 2 mg/kg, iv | Mus musculus | 3 | ALA5154877 | organism-based format | Scientific Literature | |
8. | ALA5165330 | ADME | Half life in mouse at 20 mg/kg, po | Mus musculus | 2 | ALA5154877 | organism-based format | Scientific Literature | |
9. | ALA5165331 | ADME | Half life in mouse at 2 mg/kg, iv | Mus musculus | 3 | ALA5154877 | organism-based format | Scientific Literature | |
10. | ALA5165334 | ADME | Clearance in mouse at 2 mg/kg, iv | Mus musculus | 3 | ALA5154877 | organism-based format | Scientific Literature | |
11. | ALA5165336 | ADME | Oral bioavailability in in mouse at 20 mg/kg | Mus musculus | 2 | ALA5154877 | organism-based format | Scientific Literature |