# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5155981 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell growth | Homo sapiens | 19 | ALA5154660 | cell-based format | Scientific Literature | |
2. | ALA5155982 | Functional | Antiproliferative activity against human HBL-100 cells assessed as reduction in cell growth | Homo sapiens | 19 | ALA5154660 | cell-based format | Scientific Literature | |
3. | ALA5155983 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell growth | Homo sapiens | 19 | ALA5154660 | cell-based format | Scientific Literature | |
4. | ALA5155984 | Functional | Antiproliferative activity against human SW1573 cells assessed as reduction in cell growth | Homo sapiens | 19 | ALA5154660 | cell-based format | Scientific Literature | |
5. | ALA5155985 | Functional | Antiproliferative activity against human T47D cells assessed as reduction in cell growth | Homo sapiens | 19 | ALA5154660 | cell-based format | Scientific Literature | |
6. | ALA5155986 | Functional | Antiproliferative activity against human WiDr cells assessed as reduction in cell growth | Homo sapiens | 19 | ALA5154660 | cell-based format | Scientific Literature | |
7. | ALA5155987 | Toxicity | Antiproliferative activity against human hTERT-BJ cells assessed as reduction in cell growth | Homo sapiens | 19 | ALA5154660 | cell-based format | Scientific Literature | |
8. | ALA5155988 | Functional | Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell growth measured after 48 hrs by sulforhodamine B assay | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
9. | ALA5155989 | Functional | Antiproliferative activity against human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein assessed as reduction in cell growth measured after 48 hrs by sulforhodamine B assay | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
10. | ALA5155990 | Toxicity | Antiproliferative activity against human MRC5 cells assessed as reduction in cell growth measured after 48 hrs by sulforhodamine B assay | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
11. | ALA5155991 | Functional | Resistant index, ratio of GI50 for human multi-drug resistant NCI-H460/R cells to GI50 for human NCI-H460 cells | 2 | ALA5154660 | assay format | Scientific Literature | ||
12. | ALA5155992 | Binding | Substrate activity at P-gp in human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein assessed as rhodamine 123 accumulation at 4 uM incubated for 30 mins in presence of rhodamine 123 by flow cytometry analysis | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
13. | ALA5155993 | Functional | Induction of apoptosis in human NCI-H460 cells assessed as increase in necrotic cells at 600 nM incubated for 48 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 2 %) | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
14. | ALA5155994 | Functional | Antiproliferative activity against human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein assessed as cell growth inhibition in presence of tariquidar measured after 48 hrs by sulforhodamine B assay | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
15. | ALA5155995 | Functional | Induction of apoptosis in human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein at 600 nM incubated for 48 hrs by annexin-V-FITC and PI staining based flow cytometry analysis | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
16. | ALA5155996 | Functional | Cell cycle arrest in human NCI-H460 cells assessed as decrease in accumulation at G1 phase at 600 nM measured after 48 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
17. | ALA5155997 | Functional | Cell cycle arrest in human NCI-H460 cells assessed as increase in accumulation at S phase at 600 nM measured after 48 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
18. | ALA5155998 | Functional | Cell cycle arrest in human NCI-H460 cells assessed as increase in accumulation at G2/M phase at 600 nM measured after 48 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
19. | ALA5155999 | Functional | Cell cycle arrest in human NCI-H460 cells assessed as increase in accumulation at subG1 phase at 600 nM measured after 48 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature | |
20. | ALA5156000 | Functional | Cell cycle arrest in human multi-drug resistant NCI-H460/R cells overexpressing P-glycoprotein at 600 nM measured after 48 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 2 | ALA5154660 | cell-based format | Scientific Literature |