| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5158735 | B | Inhibition of mPGES-1 activity in human A549 microsomal preparation using PGH2 as substrate preincubated for 15 mins followed by substrate addition for 1 min by RP-HPLC analysis | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 2. | ALA5158736 | B | Inhibition of human recombinant LTC4S expressed in HEK293 cell microsomal fraction preincubated for 10 mins followed by LTA4-methyl ester addition and measured after 10 mins by UPLC-MS/MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature | ||
| 3. | ALA5158739 | B | Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as inhibition of FLAP-dependent 5-LO product LTB4 formation preincubated for 15 mins followed by arachidonic acid addition and measured after 10 mins by RP-HPLC analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 4. | ALA5158740 | B | Inhibition of 5-LOX in human neutrophils assessed as reduction in FLAP-dependent 5-LO product LTB4 formation at upto 1 uM preincubated for 10 mins followed by A23187 addition and measured after 10 mins by RP-HPLC and UV detection method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA5158741 | B | Inhibition of 5-LOX in human neutrophils assessed as reduction in FLAP-dependent 5-LO product LTB4 formation at upto 10 uM preincubated for 10 mins followed by A23187 addition and measured after 10 mins by RP-HPLC and UV detection method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA5158742 | T | Cytotoxicity against human neutrophils assessed as reduction in cell viability at 10 uM by LDH release assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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