| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5154328 | F | Antiproliferative activity against human DU-145 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
| 2. | ALA5154329 | F | Induction of apoptosis in human DU-145 cells assessed as increase in cleaved PARP level at 0.003 to 0.3 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5154330 | B | Inhibition of bovine brain tubulin polymerization measured every 30 secs by absorbance based analysis | Bos taurus | 1 | assay format | Scientific Literature | ||
| 4. | ALA5154331 | B | Inhibition of tubulin polymerization in human DU-145 cells assessed as inhibition of tubulin assembly at 0.1 uM incubated for 16 hrs by Hoechst staining based confocal microscopy analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5154332 | B | Disruption of microtubule network in human DU-145 cells assessed as cell shrinkage at 0.1 uM incubated for 16 hrs by Hoechst staining based confocal microscopy analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5154333 | B | Disruption of microtubule network in human DU-145 cells assessed as reduction in acetyl-alpha tubulin expression by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5154334 | B | Disruption of microtubule network in human DU-145 cells assessed as reduction in alpha tubulin expression by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5154335 | B | Inhibition of [3H]colchicine binding to tubulin (unknown origin) at 1 uM incubated for 2 hrs by TopCount scintillation counting method relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 9. | ALA5154336 | F | Induction of G2/M phase cell cycle arrest in human DU-145 cells assessed as decrease in Cdc2 phosphorylation at T14/Y15 residue at 0.03 to 0.3 uM measured after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5154337 | F | Induction of G2/M phase cell cycle arrest in human DU-145 cells assessed as increase in cyclin B1 expression at 0.03 to 0.3 uM measured after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5154338 | F | Induction of G2/M phase cell cycle arrest in human DU-145 cells assessed as increase in histone H3 phosphorylation at Ser10 residue at 0.03 to 0.3 uM measured after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5154339 | F | Induction of apoptosis in human DU-145 cells assessed as live cells at 0.03 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 94.94%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5154340 | F | Induction of apoptosis in human DU-145 cells assessed as early apoptotic cells at 0.03 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 1.97%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5154341 | F | Induction of apoptosis in human DU-145 cells assessed as late apoptotic cells at 0.03 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 2.05%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5154342 | F | Induction of apoptosis in human DU-145 cells assessed as dead cells at 0.03 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 1.05%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5154343 | F | Induction of apoptosis in human DU-145 cells assessed as live cells at 0.1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 94.94%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5154344 | F | Induction of apoptosis in human DU-145 cells assessed as early apoptotic cells at 0.1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 1.97%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5154345 | F | Induction of apoptosis in human DU-145 cells assessed as late apoptotic cells at 0.1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 2.05%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5154346 | F | Induction of apoptosis in human DU-145 cells assessed as dead cells at 0.1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 1.05%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5154347 | F | Induction of apoptosis in human DU-145 cells assessed as live cells at 0.3 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb = 94.94%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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