# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5155953 | B | Binding affinity to human adenosine A2A receptor expressed in human HEK293 cell membrane at 10 uM by radioligand inhibition assay | Homo sapiens | 24 | ALA5154659 | cell membrane format | Scientific Literature | |
2. | ALA5155957 | B | Displacement of [125I] N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human A3A receptor stably expressed in HEK293 cell membrane by radioligand inhibition assay | Homo sapiens | 31 | ALA5154659 | cell membrane format | Scientific Literature | |
3. | ALA5155958 | F | Agonist activity at human adenosine A3A receptor stably expressed in HEK293 cells assessed as beta arrestin 2 recruitment potency by luciferase based NanoBiT assay | Homo sapiens | 11 | ALA5154659 | cell-based format | Scientific Literature | |
4. | ALA5155959 | F | Agonist activity at human adenosine A3A receptor stably expressed in HEK293 cells assessed as beta arrestin 2 recruitment maximum efficacy by luciferase based NanoBiT assay | Homo sapiens | 11 | ALA5154659 | cell-based format | Scientific Literature | |
5. | ALA5155960 | F | Agonist activity at human adenosine A3A receptor stably expressed in HEK293 cells assessed as mini G-alpha recruitment potency by luciferase based NanoBiT assay | Homo sapiens | 11 | ALA5154659 | cell-based format | Scientific Literature | |
6. | ALA5155961 | F | Agonist activity at human adenosine A3A receptor stably expressed in HEK293 cells assessed as mini G-alpha recruitment maximum efficacy by luciferase based NanoBiT assay | Homo sapiens | 11 | ALA5154659 | cell-based format | Scientific Literature | |
7. | ALA5155977 | F | Induction of hypothermia in C57BL/6 mouse assessed as reduction in core body temperature at 3 mg/kg, ip and measured upto 900 min | Mus musculus | 4 | ALA5154659 | organism-based format | Scientific Literature | |
8. | ALA5155978 | B | Displacement of [3H] N6-R-phenylisopropyladenosine from mouse A1A receptor stably expressed in HEK293 cell membrane by radioligand inhibition assay | Mus musculus | 12 | ALA5154659 | cell membrane format | Scientific Literature | |
9. | ALA5155979 | B | Displacement of [125I] N6-4-amino-3-iodobenzyl adenosine 5-N-methyluronamide from mouse A3A receptor stably expressed in HEK293 cell membrane by radioligand inhibition assay | Mus musculus | 25 | ALA5154659 | cell membrane format | Scientific Literature | |
10. | ALA5155980 | F | Induction of hypothermia in A1AR/A3AR knockout C57BL/6 mouse assessed as reduction in core body temperature at 3 mg/kg, ip and measured upto 900 min | Mus musculus | 4 | ALA5154659 | organism-based format | Scientific Literature |