# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5159807 | F | Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay | Homo sapiens | 21 | ALA5154761 | cell-based format | Scientific Literature | |
2. | ALA5159808 | F | Cytotoxicity against human A549 cells assessed as cell growth inhibition at 10 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 18 | ALA5154761 | cell-based format | Scientific Literature | |
3. | ALA5159809 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 10 uM incubated for 48 hrs by PI staining based flow cytometry analysis | Homo sapiens | 17 | ALA5154761 | cell-based format | Scientific Literature | |
4. | ALA5159810 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase incubated for 48 hrs by PI staining based flow cytometry analysis | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
5. | ALA5159811 | T | Antiproliferative activity against rat NRK-52E cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay | Rattus norvegicus | 1 | ALA5154761 | cell-based format | Scientific Literature | |
6. | ALA5159812 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability at 1 uM incubated for 4 days followed by compound washout and replacement with fresh medium without compound by cell counter method | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
7. | ALA5159813 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at Go/G1 phase at 0.5 uM incubated for 48 hrs by PI staining based flow cytometry analysis (Rvb = 62.45) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
8. | ALA5159814 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at Go/G1 phase at 1 uM incubated for 48 hrs by PI staining based flow cytometry analysis (Rvb = 62.45) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
9. | ALA5159815 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at S phase at 0.5 uM incubated for 48 hrs by PI staining based flow cytometry analysis (Rvb = 12.85%) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
10. | ALA5159816 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at S phase at 1 uM incubated for 48 hrs by PI staining based flow cytometry analysis (Rvb = 12.85%) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
11. | ALA5159817 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 0.5 uM incubated for 48 hrs by PI staining based flow cytometry analysis (Rvb = 18.14) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
12. | ALA5159818 | F | Induction of cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 1 uM incubated for 48 hrs by PI staining based flow cytometry analysis (Rvb = 18.14) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
13. | ALA5159819 | F | Induction of cell cycle arrest in human A549 cells assessed as increase in cyclin B1 expression upto 1 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
14. | ALA5159820 | F | Induction of cell cycle arrest in human A549 cells assessed as decrease in cyclin D1 expression upto 1 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
15. | ALA5159821 | F | Induction of DNA damage in human A549 cells assessed as upregulation of gamma H2AX incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
16. | ALA5159822 | F | Induction of apoptosis in human A549 cells assessed as viable cells at 0.5 uM incubated for 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 97.3%) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
17. | ALA5159823 | F | Induction of apoptosis in human A549 cells assessed as viable cells at 1 uM incubated for 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 97.3%) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
18. | ALA5159824 | F | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 0.5 uM incubated for 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 1.46%) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
19. | ALA5159825 | F | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 1 uM incubated for 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 1.46%) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature | |
20. | ALA5159826 | F | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 0.5 uM incubated for 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry analysis (Rvb = 1.00%) | Homo sapiens | 1 | ALA5154761 | cell-based format | Scientific Literature |