# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5152738 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) by fluorescence quenching assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA5152739 | B | Agonist activity at human GAL4-fused RXRalpha LBD (T225 to T462 residues) expressed in HEK293 cells incubated for 24 hrs by Dual-Glo luciferase assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA5152740 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as binding constant by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
4. | ALA5152741 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as change in enthalpy by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA5152742 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as change in entropy by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA5152743 | B | Binding affinity to human RXRalpha LBD (T225 to T462 residues) assessed as gibbs free energy change by isothermal titration calorimetry | Homo sapiens | 4 | single protein format | Scientific Literature | ||
7. | ALA5152744 | F | Induction of triglyceride level in Sprague-Dawley rat at 200 mg/kg in diet for 7 days (Rvb = 89 +/- 10 mg/dl) | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
8. | ALA5152746 | F | Induction of triglyceride level in Sprague-Dawley rat at 200 mg/kg in diet for 7 days relative to control (Rvb = 0 %) | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
9. | ALA5152769 | F | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in IL-6 level at 10 uM after 6 hrs by RT-PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
10. | ALA5152770 | F | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in IL-1beta level at 10 uM after 6 hrs by RT-PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
11. | ALA5152771 | F | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in IL27 level at 10 uM after 6 hrs by RT-PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
12. | ALA5152772 | F | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in CCL5 level at 10 uM after 6 hrs by RT-PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
13. | ALA5152773 | F | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in Saa3 level at 10 uM after 6 hrs by RT-PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
14. | ALA5152774 | F | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in CCL22 level at 10 uM after 6 hrs by RT-PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
15. | ALA5152775 | F | Antiinflammatory activity in LPS-induced mouse RAW264.7 cells assessed as reduction in Csf3 level at 10 uM after 6 hrs by RT-PCR analysis | Mus musculus | 3 | cell-based format | Scientific Literature | ||
16. | ALA5152777 | F | Prevention of UVB-induced carcinogenesis in Ptch+/- / SHK-1 mouse assessed as reduction in tumor number at 25 mg/kg measured after twice a week of UVB irradiation for 34 weeks (Rvb = 8.16 +/- 1.87) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
17. | ALA5152779 | F | Prevention of UVB-induced carcinogenesis in Ptch+/- / SHK-1 mouse assessed as reduction in tumor number at 25 mg/kg measured after twice a week of UVB irradiation for 34 weeks (Rvb = 100 %) | Mus musculus | 1 | organism-based format | Scientific Literature |