# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5117875 | A | Drug metabolism assessed as recombinant human liver CYP2C19-mediated formation of desmethyl-zicronapine at 10 uM measured after 15 to 180 mins in presence of zicronapine by LC-MS/MS analysis | Homo sapiens | 2 | ALA5113485 | tissue-based format | Scientific Literature | |
2. | ALA5117876 | A | Drug metabolism assessed as recombinant human liver CYP2C19-mediated formation of d5-desmethyl-zicronapine at 10 uM measured after 15 to 180 mins in presence of zicronapine by LC-MS/MS analysis | Homo sapiens | 2 | ALA5113485 | tissue-based format | Scientific Literature | |
3. | ALA5117881 | A | Drug metabolism assessed as recombinant human liver CYP3A4-mediated formation of desmethyl-zicronapine at 10 uM measured after 15 to 180 mins in presence of zicronapine by LC-MS/MS analysis | Homo sapiens | 2 | ALA5113485 | tissue-based format | Scientific Literature | |
4. | ALA5117882 | A | Drug metabolism assessed as recombinant human liver CYP3A4-mediated formation of d5-desmethyl-zicronapine at 10 uM measured after 15 to 180 mins in presence of zicronapine by LC-MS/MS analysis | Homo sapiens | 2 | ALA5113485 | tissue-based format | Scientific Literature | |
5. | ALA5117883 | B | Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
6. | ALA5117884 | A | Drug metabolism in human liver microsomes assessed as formation of desmethyl-zicronapine at 10 uM measured after 15 to 180 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 2 | ALA5113485 | microsome format | Scientific Literature | |
7. | ALA5117885 | A | Drug metabolism in human liver microsomes assessed as formation of d5-desmethyl-zicronapine at 10 uM measured after 15 to 180 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Homo sapiens | 2 | ALA5113485 | microsome format | Scientific Literature | |
8. | ALA5117886 | B | Displacement of [125I]CYP from rat brain 5HT1B receptor measured after 120 mins by scintillation counting analysis | Rattus norvegicus | 2 | ALA5113485 | assay format | Scientific Literature | |
9. | ALA5117887 | B | Displacement of [125I](+/-)DOI from recombinant human 5-HT2A receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
10. | ALA5117888 | B | Displacement of [125I](+/-)DOI from recombinant human 5-HT2B receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
11. | ALA5117889 | B | Displacement of [125I](+/-)DOI from recombinant human 5-HT2C receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
12. | ALA5117890 | B | Displacement of [3H]LSD from recombinant human 5-HT6 receptor measured after 120 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
13. | ALA5117891 | B | Displacement of [3H]LSD from recombinant human 5-HT7 receptor measured after 120 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
14. | ALA5117892 | B | Displacement of [3H]SCH 23390 from recombinant human D1 receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
15. | ALA5117893 | B | Displacement of [3H]7-OH-DPAT from recombinant human D2S receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
16. | ALA5117894 | B | Displacement of [3H]methyl-spiperone from recombinant human D3 receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
17. | ALA5117895 | B | Displacement of [3H]methyl-spiperone from recombinant human D4.4 receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
18. | ALA5117896 | B | Displacement of [3H]SCH 23390 from recombinant human D5 receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
19. | ALA5117897 | B | Displacement of [3H]prazosin from recombinant human alpha1A receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature | |
20. | ALA5117898 | B | Displacement of [3H]prazosin from recombinant human alpha1B receptor measured after 60 mins by scintillation counting analysis | Homo sapiens | 2 | ALA5113485 | single protein format | Scientific Literature |