# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5120624 | Binding | Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-2 stimulation for 15 mins by FACS method | Homo sapiens | 33 | ALA5113550 | cell-based format | Scientific Literature | |
2. | ALA5120626 | ADME | Plasma protein binding in rat | Rattus norvegicus | 4 | ALA5113550 | cell-free format | Scientific Literature | |
3. | ALA5120627 | ADME | Plasma protein binding in human | Homo sapiens | 4 | ALA5113550 | cell-free format | Scientific Literature | |
4. | ALA5120628 | Functional | Inhibition of IL-2 stimulated IFN-gamma production in BALB/c mouse at 40 mg/kg, po pretreated for 30 mins followed by IL-2 stimulation and measured after 4 hrs by ELISA | Mus musculus | 15 | ALA5113550 | organism-based format | Scientific Literature |