#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5167700	A	Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate incubated for 5 to 45 mins in presence of NADPH by LC/MS analysis	Homo sapiens	3	ALA5154926	microsome format	Scientific Literature
2.	ALA5167703	F	Antiproliferative activity against human HCT-116 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	52	ALA5154926	cell-based format	Scientific Literature
3.	ALA5167704	F	Antiproliferative activity against human HT-29 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	7	ALA5154926	cell-based format	Scientific Literature
4.	ALA5167705	F	Antiproliferative activity against human SW-620 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	7	ALA5154926	cell-based format	Scientific Literature
5.	ALA5167706	F	Antiproliferative activity against human DLD-1 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	7	ALA5154926	cell-based format	Scientific Literature
6.	ALA5167707	B	Agonist activity at human CLpP (57 to 277 amino acids) expressed in Escherichia coli using fluorogenic peptide AC-WLA-AMC as substrate incubated for 10 mins by fluorescence based assay	Homo sapiens	52	ALA5154926	assay format	Scientific Literature
7.	ALA5167708	B	Binding affinity to human CLpP (57 to 277 amino acids) expressed in Escherichia coli assessed as change in melting temperature at 100 uM incubated for 30 mins by DSF assay	Homo sapiens	2	ALA5154926	assay format	Scientific Literature
8.	ALA5167710	F	Antiproliferative activity against human HCT-15 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	7	ALA5154926	cell-based format	Scientific Literature
9.	ALA5167711	F	Antiproliferative activity against human SW480 cells incubated for 48 hrs by CCK-8 assay	Homo sapiens	7	ALA5154926	cell-based format	Scientific Literature
10.	ALA5167714	B	Binding affinity to CLpP in human HCT-116 cells assessed as protein stabilization at 10 uM incubated for 30 mins followed by heating at 46 to 74 degree celcius for 3 mins CETSA based Western blot analysis	Homo sapiens	2	ALA5154926	cell-based format	Scientific Literature
11.	ALA5167715	B	Binding affinity to human CLpP assessed as dissociation constant by ITC method	Homo sapiens	2	ALA5154926	single protein format	Scientific Literature
12.	ALA5167716	B	Binding affinity to human CLpP assessed as change in entropy by ITC method	Homo sapiens	2	ALA5154926	single protein format	Scientific Literature
13.	ALA5167717	B	Binding affinity to human CLpP assessed as change in enthalpy by ITC method	Homo sapiens	2	ALA5154926	single protein format	Scientific Literature
14.	ALA5167718	B	Potency index, ratio of ONC201 Kd to test compound Kd for binding affinity to human CLpP	Homo sapiens	1	ALA5154926	single protein format	Scientific Literature
15.	ALA5167719	B	Binding affinity to human CLpP Y138F/Q107A double mutant assessed as dissociation constant by ITC method	Homo sapiens	2	ALA5154926	assay format	Scientific Literature
16.	ALA5167720	B	Ratio of Kd for human CLpP to Kd for human CLpP Y138F/Q107A double mutant assessed as dissociation constant	Homo sapiens	2	ALA5154926	assay format	Scientific Literature
17.	ALA5167721	B	Binding affinity to human CLpP Y138F/Q107A double mutant assessed as change in enthalpy by ITC method	Homo sapiens	2	ALA5154926	assay format	Scientific Literature
18.	ALA5167722	B	Binding affinity to human CLpP Y138F/Q107A double mutant assessed as change in entropy by ITC method	Homo sapiens	2	ALA5154926	assay format	Scientific Literature
19.	ALA5167723	F	Induction of ROS generation in human HCT-116 cells measured after 24 hrs by DHE staining based fluorescence assay	Homo sapiens	1	ALA5154926	cell-based format	Scientific Literature
20.	ALA5167724	F	Induction of mitochondrial membrane potential loss in human HCT-116 cells measured after 48 hrs by TMRM staining based fluorescence assay	Homo sapiens	1	ALA5154926	cell-based format	Scientific Literature