| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5152828 | F | Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability at 20 uM incubated for 24 hrs by CCK-8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA5152829 | F | Antiproliferative activity against human K562 cells assessed as reduction in cell viability at 20 uM incubated for 24 hrs by CCK-8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA5152830 | F | Antiproliferative activity against human A498 cells assessed as reduction in cell viability at 20 uM incubated for 24 hrs by CCK-8 assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA5152831 | F | Antiproliferative activity against human HL-60 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA5152832 | F | Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA5152833 | F | Antiproliferative activity against human A498 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA5152834 | T | Cytotoxicity against human NCM460 cells assessed as inhibition of cell growth | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA5152835 | B | PROTAC activity at VHL/GSPT1 in human HL-60 cells assessed as effect on GSPT1 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA5152836 | B | PROTAC activity at VHL/GSPT1 in human K562 cells assessed as effect on GSPT1 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA5152837 | B | PROTAC activity at VHL/GSPT1 in human A498 cells assessed as effect on GSPT1 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA5152838 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 10 to 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5152839 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 10 uM incubated for 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5152840 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 10 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5152841 | B | PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at >10 uM measured at 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5152842 | B | PROTAC activity at VHL/FLT-3 in human K562 cells assessed as reduction in FLT-3 protein level at 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA5152844 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 1 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5152845 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5152846 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM preincubated with MG-132 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5152847 | B | PROTAC activity at VHL/FLT-3 in human HL-60 cells assessed as reduction in FLT-3 protein level at 20 uM preincubated with VHL032 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5152848 | B | PROTAC activity at VHL/c-KIT in human HL-60 cells assessed as reduction in c-KIT protein level at 20 uM preincubated with VHL032 for 1 hrs followed by compound addition and measured after for 48 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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