#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5131231	Binding	Inhibition of TYK2 JH2 domain (unknown origin) assessed as melting temperature at 10 uM by thermal shift assay	Homo sapiens	29	ALA5126671	single protein format	Scientific Literature
2.	ALA5131232	Binding	Inhibition of TYK2 JH2 domain (unknown origin) assessed as melting temperature at 1 uM by thermal shift assay	Homo sapiens	29	ALA5126671	single protein format	Scientific Literature
3.	ALA5131233	Binding	Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assay	Homo sapiens	29	ALA5126671	cell-based format	Scientific Literature
4.	ALA5131234	ADME	Stability in human liver microsomes assessed as parent compound remaining after 60 mins in presence of NADPH+	Homo sapiens	22	ALA5126671	microsome format	Scientific Literature
5.	ALA5131235	ADME	Stability in mouse liver microsomes assessed as parent compound remaining after 60 mins in presence of NADPH+	Mus musculus	22	ALA5126671	microsome format	Scientific Literature
6.	ALA5131236	Binding	Inhibition of JAK1 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assay	Homo sapiens	1	ALA5126671	single protein format	Scientific Literature
7.	ALA5131237	Binding	Inhibition of JAK2 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assay	Homo sapiens	1	ALA5126671	single protein format	Scientific Literature
8.	ALA5131238	Binding	Inhibition of JAK3 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assay	Homo sapiens	1	ALA5126671	single protein format	Scientific Literature
9.	ALA5131239	Binding	Inhibition of TYK2 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assay	Homo sapiens	1	ALA5126671	single protein format	Scientific Literature
10.	ALA5131240	Binding	Inhibition of JAK2 in platelet cells (unknown origin) assessed as reduction in EPO stimulated STAT3 phosphorylation by HTRF assay	Homo sapiens	1	ALA5126671	cell-based format	Scientific Literature
11.	ALA5131241	Binding	Inhibition of JAK1/JAK3 in CD3+ T cells (unknown origin) assessed as reduction in IL-2 stimulated STAT5 phosphorylation incubated for 1.5 hrs by HTRF assay	Homo sapiens	1	ALA5126671	cell-based format	Scientific Literature
12.	ALA5131242	Binding	Inhibition of JAK1/JAK3 in CD3+ T cells (unknown origin) assessed as reduction in IL-6 stimulated STAT3 phosphorylation incubated for 1.5 hrs by HTRF assay	Homo sapiens	1	ALA5126671	cell-based format	Scientific Literature
13.	ALA5131243	Binding	Binding affinity to T7-tagged TYK2 JH2 (unknown origin) expressed in Escherichia coli BL21 cells incubated for 1 hr by qPCR analysis	Homo sapiens	1	ALA5126671	cell-based format	Scientific Literature
14.	ALA5131244	ADME	Tmax in mouse at 20 mg/kg, ig measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA5126671	organism-based format	Scientific Literature
15.	ALA5131245	ADME	Cmax in mouse at 20 mg/kg, ig measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA5126671	organism-based format	Scientific Literature
16.	ALA5131246	ADME	AUC(0 to t) in mouse at 20 mg/kg, ig measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA5126671	organism-based format	Scientific Literature
17.	ALA5131247	ADME	AUC(0 to infinity) in mouse at 20 mg/kg, ig measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA5126671	organism-based format	Scientific Literature
18.	ALA5131248	ADME	Half life in mouse at 20 mg/kg, ig measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA5126671	organism-based format	Scientific Literature
19.	ALA5131249	ADME	MRT(0 to t) in mouse at 20 mg/kg, ig measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA5126671	organism-based format	Scientific Literature
20.	ALA5131250	ADME	Bioavailability in mouse at 20 mg/kg, ig measured up to 24 hrs by LC-MS/MS analysis	Mus musculus	1	ALA5126671	organism-based format	Scientific Literature