# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5125951 | B | Binding affinity to bovine serum albumin assessed as increase in fluorescence intensity at 10 uM measured after 4 hrs by TAMRA-N3 based In-gel fluorescence scanning analysis | Bos taurus | 4 | ALA5120948 | single protein format | Scientific Literature | |
2. | ALA5125953 | B | Inhibition of EGFR L858R mutant (unknown origin) using peptide substrate by FRET assay | Homo sapiens | 1 | ALA5120948 | single protein format | Scientific Literature | |
3. | ALA5125954 | B | Inhibition of wild type EGFR (unknown origin) using peptide substrate by FRET assay | Homo sapiens | 1 | ALA5120948 | single protein format | Scientific Literature | |
4. | ALA5125955 | B | Inhibition of TRKC (unknown origin) using peptide substrate by FRET assay | Homo sapiens | 1 | ALA5120948 | single protein format | Scientific Literature | |
5. | ALA5125956 | B | Inhibition of SRC (unknown origin) using peptide substrate by FRET assay | Homo sapiens | 1 | ALA5120948 | single protein format | Scientific Literature | |
6. | ALA5125957 | B | Inhibition of Abl kinase (unknown origin) using peptide substrate by FRET assay | Homo sapiens | 1 | ALA5120948 | single protein format | Scientific Literature | |
7. | ALA5125958 | F | Growth inhibition of mouse BaF3 cells harbouring EGFR L858R mutant incubated for 72 hrs by CCK8 assay | Mus musculus | 1 | ALA5120948 | cell-based format | Scientific Literature | |
8. | ALA5125959 | F | Growth inhibition of mouse Ba/F3 EGFR cells incubated for 72 hrs by CCK8 assay | Mus musculus | 1 | ALA5120948 | cell-based format | Scientific Literature | |
9. | ALA5125960 | F | Growth inhibition of human NCI-H3255 cells harbouring EGFR L858R mutant incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA5120948 | cell-based format | Scientific Literature | |
10. | ALA5125961 | F | Growth inhibition of human A549 cells expressing EGFR incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | ALA5120948 | cell-based format | Scientific Literature | |
11. | ALA5125962 | B | Binding affinity to EGFR L858R mutant in human NCI-H3255 cells at 10 uM incubated for 8 hrs by pull-down/Western blot analysis | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
12. | ALA5125963 | B | Binding affinity to EGFR L858R mutant in mouse BaF3 cells at 10 uM incubated for 8 hrs by pull-down/Western blot analysis | Mus musculus | 1 | ALA5120948 | cell-based format | Scientific Literature | |
13. | ALA5125964 | B | Binding affinity to EGFR L858R mutant in human NCI-H3255 cells at 10 uM incubated for 8 hrs in presence of afatinib by pull-down/Western blot analysis | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
14. | ALA5125965 | B | Binding affinity to EGFR L858R mutant in human NCI-H3255 cells assessed as increase in thermal stability at 0.5 uM incubated for 3 hrs by cellular thermal shift assay | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
15. | ALA5125966 | F | Inhibition of colony formation in human NCI-H3255 cells at 1.1 uM by Giemsa staining based assay | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
16. | ALA5125967 | B | Inhibition of EGFR phosphorylation in human NCI-H3255 cells at 0.22 to 20 uM | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
17. | ALA5125968 | B | Inhibition of EGFR in human NCI-H3255 cells assessed as decrease in AKT phosphorylation level at 0.22 to 20 uM | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
18. | ALA5125969 | B | Inhibition of EGFR in human NCI-H3255 cells assessed as decrease in ERK phosphorylation level at 0.22 to 20 uM | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
19. | ALA5125982 | B | Binding affinity to MDR1 in human HepG2 cells at 10 uM incubated for 8 hrs by pull-down/LC-MS/MS analysis | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature | |
20. | ALA5125983 | B | Binding affinity to LPPRC in human HepG2 cells at 10 uM incubated for 8 hrs by pull-down/LC-MS/MS analysis | Homo sapiens | 1 | ALA5120948 | cell-based format | Scientific Literature |