| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5122387 | B | Covalent modification of N-terminus mouse recombinant RELA (1 to 325 residues) assessed as high molecular weight band formation at 1:1 protein to compound concentration measured after 24 hrs by SDS-PAGE based silver staining analysis | Mus musculus | 1 | ALA5120809 | single protein format | Scientific Literature | |
| 2. | ALA5122388 | F | Antiproliferative activity against human A2780 cells assessed as cell growth inhibition measured after 3 days by cell viability assay | Homo sapiens | 14 | ALA5120809 | cell-based format | Scientific Literature | |
| 3. | ALA5122389 | F | Antiproliferative activity against human OVCAR-5 cells assessed as cell growth inhibition measured after 3 days by cell viability assay | Homo sapiens | 14 | ALA5120809 | cell-based format | Scientific Literature | |
| 4. | ALA5122390 | F | Antiproliferative activity against human MIA PaCa-2 cells assessed as cell growth inhibition measured after 3 days by cell viability assay | Homo sapiens | 14 | ALA5120809 | cell-based format | Scientific Literature | |
| 5. | ALA5122391 | B | Covalent modification of N-terminal hexa-his-tagged human recombinant IKKbeta assessed as high molecular weight band formation at 1:1 protein to compound concentration measured after 24 hrs by SDS-PAGE based silver staining analysis | Homo sapiens | 1 | ALA5120809 | single protein format | Scientific Literature | |
| 6. | ALA5122392 | B | Covalent modification of N-terminal hexa-his-tagged human recombinant IKKbeta/ N-terminus mouse recombinant RELA (1 to 325 residues) assessed as tertiary complex formation with RELA by measuring high molecular weight band formation at 1:1:1 protein/protein to compound concentration measured after 24 hrs by SDS-PAGE based silver staining analysis | Homo sapiens | 1 | ALA5120809 | assay format | Scientific Literature | |
| 7. | ALA5122393 | B | Covalent modification of N-terminus mouse recombinant RELA (1 to 325 residues) assessed as high molecular weight band formation at 1:10 protein to compound concentration measured after 24 hrs by SDS-PAGE based silver staining analysis | Mus musculus | 1 | ALA5120809 | single protein format | Scientific Literature | |
| 8. | ALA5122394 | B | Covalent modification of N-terminal hexa-his-tagged human recombinant IKKbeta assessed as high molecular weight band formation at 1:10 protein to compound concentration measured after 24 hrs by SDS-PAGE based silver staining analysis | Homo sapiens | 1 | ALA5120809 | single protein format | Scientific Literature | |
| 9. | ALA5122395 | B | Covalent modification of RELA in human OVCAR-5 cells assessed as high molecular weight band formation incubated for 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 10. | ALA5122396 | B | Covalent modification of RELA in human OVCAR-5 cells assessed as increase in PARP cleavage at 10 uM incubated for 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 11. | ALA5122397 | B | Covalent modification of RELA in human FT282C11 cells assessed as high molecular weight band formation at 10 uM incubated for 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 12. | ALA5122398 | B | Covalent modification of RELA in human MIA PaCa-2 cells assessed as high molecular weight band formation at 10 uM incubated for 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 13. | ALA5122399 | B | Covalent modification of RELA in human OVCAR-5 cells assessed as high molecular weight band formation at 10 uM incubated for 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 14. | ALA5122400 | B | Covalent modification of RELA in human MIA PaCa-2 cells assessed as increase in PARP cleavage at 10 uM incubated for 2 hrs by Western blot analysis | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 15. | ALA5122401 | B | Covalent modification of RELA in TNF-alpha induced human OVCAR-5 cells assessed as inhibition of phosphorylation of IkappaB-alpha at 10 uM pretreated for 2 hrs followed by TNF-alpha stimulation for 10 mins by Western blot analysis | Homo sapiens | 2 | ALA5120809 | cell-based format | Scientific Literature | |
| 16. | ALA5122402 | B | Covalent modification of RELA in TNF-alpha induced human OVCAR-5 cells assessed as inhibition of nuclear localization of protein at 10 uM pretreated for 2 hrs followed by TNF-alpha stimulation for 10 mins by Western blot analysis | Homo sapiens | 2 | ALA5120809 | cell-based format | Scientific Literature | |
| 17. | ALA5122403 | B | Inhibition of TNF-alpha induced RELA in human A549 cells assessed as reduction in NFkappaB mediated gene expression pretreated for 2 hrs followed by TNF-alpha stimulation for 3 hrs by Alamar blue based analysis | Homo sapiens | 2 | ALA5120809 | cell-based format | Scientific Literature | |
| 18. | ALA5122404 | F | Inhibition of colony formation in human A2780 cells measured every day up to 4 days by IncuCyte live-cell imaging assay | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 19. | ALA5122405 | F | Antiproliferative activity against human OVCAR-5 cells assessed as cell growth inhibition at 1.11 to 10 uM incubated for 6 hrs followed by compound removal and measured up to 72 hrs by IncuCyte live-cell imaging assay | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature | |
| 20. | ALA5122406 | F | Inhibition of cell migration in human A2780 cells at 500 nM measured up to 48 hrs by wound healing scratch assay | Homo sapiens | 1 | ALA5120809 | cell-based format | Scientific Literature |
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