# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5119286 | B | Inhibition of HDAC in human HeLa nuclear extract incubated for 30 mins by fluorescence-based Glo-luminescence assay | Homo sapiens | 14 | ALA5113518 | cell-based format | Scientific Literature | |
2. | ALA5119288 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA Pu22 (unknown origin) by fluorescence quench assay | Not specified | 17 | ALA5113518 | nucleic acid format | Scientific Literature | |
3. | ALA5119290 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA Pu22 (unknown origin) assessed as change in melting temperature at 1 uM by fluorescence resonance energy transfer assay | Not specified | 19 | ALA5113518 | nucleic acid format | Scientific Literature | |
4. | ALA5119291 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 48 hrs | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
5. | ALA5119292 | F | Cytotoxicity against human SUM159PT cells assessed as reduction in cell viability measured after 48 hrs | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
6. | ALA5119293 | F | Cytotoxicity against human BT-549 cells assessed as reduction in cell viability measured after 48 hrs | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
7. | ALA5119294 | B | Inhibition of full length recombinant C-terminal GST-tagged human HDAC1 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by Glo- luminescence assay | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
8. | ALA5119295 | B | Inhibition of full length recombinant N-terminal GST-tagged human HDAC8 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by Glo- luminescence assay | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
9. | ALA5119296 | B | Inhibition of full length recombinant N-terminal GST-tagged human HDAC4 (612 to end residues)expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by Glo- luminescence assay | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
10. | ALA5119297 | B | Inhibition of full length recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by Glo- luminescence assay | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
11. | ALA5119298 | B | Inhibition of full length recombinant N-terminal GST-tagged human HDAC11 expressed in baculovirus infected Sf9 insect cells incubated for 50 mins by Glo- luminescence assay | Homo sapiens | 2 | ALA5113518 | cell-based format | Scientific Literature | |
12. | ALA5119299 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA Pu22 (unknown origin) assessed as dissociation constant by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
13. | ALA5119300 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA HRAS (unknown origin) assessed as dissociation constant by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
14. | ALA5119301 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA HTG21 (unknown origin) assessed as dissociation constant by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
15. | ALA5119302 | B | Binding affinity to 5' FAM-labeled c-myc G4-quadruplex DNA duplex (unknown origin) assessed as dissociation constant at 10 uM by surface plasmon resonance assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
16. | ALA5119303 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA HRAS (unknown origin) assessed as change in melting temperature by fluorescence resonance energy transfer assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
17. | ALA5119304 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA HTG21 (unknown origin) assessed as change in melting temperature by fluorescence resonance energy transfer assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
18. | ALA5119305 | B | Binding affinity to 5' FAM and 3' TAMRA-labeled c-myc G4-quadruplex DNA duplex (unknown origin) assessed as change in melting temperature by fluorescence resonance energy transfer assay | Not specified | 2 | ALA5113518 | nucleic acid format | Scientific Literature | |
19. | ALA5119306 | B | Stabilization of DNA Pu22 (unknown origin ) single strand assessed as G4-quadruplex formation up to 30 uM in presence of potassium ions by spectrum based circular dichroism analysis | Not specified | 2 | ALA5113518 | assay format | Scientific Literature | |
20. | ALA5119307 | B | Stabilization of DNA Pu22 (unknown origin ) single strand assessed as G4-quadruplex formation in absence of potassium ions by spectrum based circular dichroism analysis | Not specified | 2 | ALA5113518 | assay format | Scientific Literature |