#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5160511	Binding	Inhibition of IDO1 in IFN gamma-stimulated human HeLa cells measured after 48 hrs by fluorescence based microplate reader assay	Homo sapiens	16	ALA5154775	cell-based format	Scientific Literature
2.	ALA5160512	Binding	Inhibition of IDO1 in IFNgamma/LPS stimulated human whole blood assessed as unbound concentration using kynurenine/tryptophan as substrate preincubated with compound for 15 mins followed by incubation with IFNgamma/LPS for 18 hrs by LC/MS/MS analysis	Homo sapiens	8	ALA5154775	tissue-based format	Scientific Literature
3.	ALA5160513	Toxicity	Inhibition of MK-499 binding to hERG	Homo sapiens	10	ALA5154775	assay format	Scientific Literature
4.	ALA5160514	Physicochemical	Solubility of compound at pH 2		10	ALA5154775	small-molecule physicochemical format	Scientific Literature
5.	ALA5160515	Physicochemical	Solubility of compound at pH 7		11	ALA5154775	small-molecule physicochemical format	Scientific Literature
6.	ALA5160516	ADME	Unbound intrinsic clearance in human hepatocytes	Homo sapiens	9	ALA5154775	cell-based format	Scientific Literature
7.	ALA5160517	ADME	Unbound intrinsic clearance in rat hepatocytes	Rattus norvegicus	9	ALA5154775	cell-based format	Scientific Literature
8.	ALA5160521	ADME	Inhibition of CYP2C9 (unknown origin)	Homo sapiens	4	ALA5154775	single protein format	Scientific Literature
9.	ALA5160523	Binding	Displacement of [3H] labeled-N-(4-Fluorophenyl)-3-(4-(4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl)phenyl)oxetane-3-carboxamide from human IDO1 assessed as inhibition constant by radioligand binding assay	Homo sapiens	2	ALA5154775	single protein format	Scientific Literature
10.	ALA5160524	Binding	Displacement of [3H] labeled-N-(4-Fluorophenyl)-3-(4-(4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl)phenyl)oxetane-3-carboxamide from human IDO1 assessed as dissociation rate constant by radioligand binding assay	Homo sapiens	1	ALA5154775	single protein format	Scientific Literature
11.	ALA5160525	Binding	Displacement of [3H] labeled-N-(4-Fluorophenyl)-3-(4-(4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl)phenyl)oxetane-3-carboxamide from human IDO1 assessed as dissociation half life by radioligand binding assay	Homo sapiens	1	ALA5154775	single protein format	Scientific Literature
12.	ALA5160526	Functional	In vivo inhibition of human IDO1 knock-in mouse CT26 cells translated in single oral gavage dosed CD1 mouse tumor model assessed as reduction in kynurenine level in tumor measured upto 24 hrs	Mus musculus	1	ALA5154775	organism-based format	Scientific Literature
13.	ALA5160527	Functional	In vivo inhibition of human IDO1 knock-in mouse CT26 cells translated in single oral gavage dosed CD1 mouse tumor model assessed as reduction in kynurenine level in plasma measured upto 24 hrs	Mus musculus	1	ALA5154775	organism-based format	Scientific Literature
14.	ALA5160528	Binding	Inhibition of potassium channel (unknown origin) current	Homo sapiens	1	ALA5154775	assay format	Scientific Literature
15.	ALA5160529	Binding	Inhibition of Sodium channel (unknown origin) current	Homo sapiens	1	ALA5154775	assay format	Scientific Literature
16.	ALA5160530	Binding	Inhibition of Calcium channel (unknown origin) current	Homo sapiens	1	ALA5154775	assay format	Scientific Literature
17.	ALA5160531	ADME	Clearance in Wistar Han rat at 1 mg/kg, po or 0.5 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	1	ALA5154775	organism-based format	Scientific Literature
18.	ALA5160532	ADME	Clearance in dog at 0.5 mg/kg, po or 0.25 mg/kg, iv by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5154775	organism-based format	Scientific Literature
19.	ALA5160533	ADME	Half life in Wistar Han rat at 1 mg/kg, po or 0.5 mg/kg, iv by LC-MS/MS analysis	Rattus norvegicus	1	ALA5154775	organism-based format	Scientific Literature
20.	ALA5160534	ADME	Half life in dog at 0.5 mg/kg, po or 0.25 mg/kg, iv by LC-MS/MS analysis	Canis lupus familiaris	1	ALA5154775	organism-based format	Scientific Literature