# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5167630 | A | Microsomal stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 4 | ALA5154925 | microsome format | Scientific Literature | |
2. | ALA5167632 | B | Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assay | Homo sapiens | 30 | ALA5154925 | single protein format | Scientific Literature | |
3. | ALA5167633 | B | Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assay | Homo sapiens | 30 | ALA5154925 | single protein format | Scientific Literature | |
4. | ALA5167634 | B | Selectivity ratio of IC50 for PI3Kalpha (unknown origin) to IC50 for PI3Kdelta (unknown origin) | Homo sapiens | 30 | ALA5154925 | assay format | Scientific Literature | |
5. | ALA5167635 | B | Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assay | Homo sapiens | 4 | ALA5154925 | single protein format | Scientific Literature | |
6. | ALA5167636 | B | Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate measured after 1 hr in presence of ATP by ADP-glo luminescence assay | Homo sapiens | 4 | ALA5154925 | single protein format | Scientific Literature | |
7. | ALA5167637 | B | Inhibition of mTOR (unknown origin) | Homo sapiens | 4 | ALA5154925 | single protein format | Scientific Literature | |
8. | ALA5167638 | B | Inhibition of PI3Kdelta in IgM stimulated human Raji cells incubated for 10 mins by AlphaLISA assay | Homo sapiens | 4 | ALA5154925 | cell-based format | Scientific Literature | |
9. | ALA5167639 | B | Inhibition of PI3Kalpha in IGF-1 stimulated mouse C2C12 cells incubated for 10 mins by AlphaLISA assay | Mus musculus | 4 | ALA5154925 | cell-based format | Scientific Literature | |
10. | ALA5167640 | B | Inhibition of PI3Kbeta in LPA stimulated human PC-3 cells incubated for 10 mins by AlphaLISA assay | Homo sapiens | 4 | ALA5154925 | cell-based format | Scientific Literature | |
11. | ALA5167641 | B | Inhibition of PI3Kgamma in C5a stimulated mouse RAW264.7 cells incubated for 10 mins by AlphaLisa assay | Mus musculus | 4 | ALA5154925 | cell-based format | Scientific Literature | |
12. | ALA5167645 | P | Solubility of the compound in PBS | 4 | ALA5154925 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA5167646 | A | Plasma protein binding in mouse | Mus musculus | 4 | ALA5154925 | cell-free format | Scientific Literature | |
14. | ALA5167647 | A | Microsomal stability in mouse liver microsomes assessed as half life | Mus musculus | 4 | ALA5154925 | microsome format | Scientific Literature | |
15. | ALA5167648 | P | Solubility of the compound in FaSSIF | 4 | ALA5154925 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA5167649 | P | Permeability constant, logPe of the compound | 4 | ALA5154925 | small-molecule physicochemical format | Scientific Literature |