| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5163214 | B | Inhibition of alpha2c adrenergic receptor (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 2. | ALA5163232 | B | Inhibition of PRC2 (unknown origin) assessed as reduction in H3K27 trimethylation using H3K27Me0 peptide (21 to 44 residues) as substrate by measuring SAH formation by LC-MS analysis | Homo sapiens | 15 | assay format | Scientific Literature | ||
| 3. | ALA5163235 | B | Inhibition of PRC2 in human G-401 cells assessed as H3K27 methylation status incubated for 48 hrs by ELISA method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA5163236 | F | Antiproliferative activity against human KARPAS-422 cells expressing EZH2 mutant assessed as inhibition of cell growth after 14 days by beckman coulter counting method | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA5163237 | P | Lipophilicity, logD of the compound at pH 7.4 by LC with tandem MS analysis | 5 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA5163238 | P | Dissociation constant, pKa of compound | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA5163239 | P | High throughput solubility of the compound at pH 6.8 after 16 to 24 hrs by MS/MS analysis | 9 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA5163245 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 5 | microsome format | Scientific Literature | ||
| 9. | ALA5163246 | A | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 5 | microsome format | Scientific Literature | ||
| 10. | ALA5163247 | A | Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate incubated for 10 mins in presence of NADPH by LC-MS/MS analysis | Homo sapiens | 11 | microsome format | Scientific Literature | ||
| 11. | ALA5163248 | B | Inhibition of human Phosphodiesterase 4D | Homo sapiens | 4 | single protein format | Scientific Literature |
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