# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5128988 | T | Cytotoxicity against adipocyte differentiated mouse 3T3-L1 cells at 100 uM by MTT assay | Mus musculus | 9 | cell-based format | Scientific Literature | ||
2. | ALA5128989 | F | Upregulation of PPARgamma mRNA expression in adipocyte differentiated mouse 3T3-L1 cells assessed as fold increase in PPARgamma expression at 10 uM measured after 24 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA5128991 | F | Upregulation of PPARalpha mRNA expression in adipocyte differentiated mouse 3T3-L1 cells assessed as fold increase in PPARalpha expression at 10 uM measured after 24 hrs | Mus musculus | 3 | cell-based format | Scientific Literature | ||
4. | ALA5128992 | F | Upregulation of GLUT-4 mRNA expression in adipocyte differentiated mouse 3T3-L1 cells at 10 uM measured after 24 hrs | Mus musculus | 6 | cell-based format | Scientific Literature | ||
5. | ALA5128993 | F | Antidiabetic activity in nicotinamide and streptozotocin induced hyperglycemic mouse model assessed as reduction in blood glucose at 100 mg/kg, IG administered as single dose and measured after 7 hrs | Mus musculus | 3 | organism-based format | Scientific Literature | ||
6. | ALA5128994 | F | Antidiabetic activity in nicotinamide and streptozotocin induced hyperglycemic mouse model assessed as reduction in triglyceride level at 100 mg/kg, IG administered as single dose and measured on day 0 (Rvb = 92 +/- 10 mg/dl) | Mus musculus | 4 | organism-based format | Scientific Literature | ||
7. | ALA5128995 | F | Antidiabetic activity in nicotinamide and streptozotocin induced hyperglycemic mouse model assessed as reduction in triglyceride level at 100 mg/kg, IG administered as single dose and measured on day 1 (Rvb = 88 +/- 6 mg/dl) | Mus musculus | 4 | organism-based format | Scientific Literature | ||
8. | ALA5128996 | F | Antidiabetic activity in nicotinamide and streptozotocin induced hyperglycemic mouse model assessed as reduction in triglyceride level at 100 mg/kg, IG administered as single dose and measured on day 3 (Rvb = 95 +/- 5 mg/dl) | Mus musculus | 4 | organism-based format | Scientific Literature | ||
9. | ALA5128997 | F | Antidiabetic activity in nicotinamide and streptozotocin induced hyperglycemic mouse model assessed as reduction in triglyceride level at 100 mg/kg, IG administered as single dose and measured on day 5 (Rvb = 93 +/- 10 mg/dl) | Mus musculus | 4 | organism-based format | Scientific Literature | ||
10. | ALA5128998 | B | Binding affinity to PPARgamma (unknown origin) assessed as change in binding free energy | Homo sapiens | 4 | single protein format | Scientific Literature | ||
11. | ALA5128999 | P | Lipophilicity, logP of compound | 4 | small-molecule physicochemical format | Scientific Literature |