# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5117106 | B | Inhibition of rat nNOS using L-arginine as substrate assessed as reduction in NO production in the presence of NADPH by NO-hemoglobin capture assay | Rattus norvegicus | 11 | ALA5113456 | single protein format | Scientific Literature | |
2. | ALA5117107 | B | Inhibition of human nNOS using L-arginine as substrate assessed as reduction in NO production in the presence of NADPH by NO-hemoglobin capture assay | Homo sapiens | 11 | ALA5113456 | single protein format | Scientific Literature | |
3. | ALA5117108 | B | Inhibition of human iNOS using L-arginine as substrate assessed as reduction in NO production in the presence of NADPH by NO-hemoglobin capture assay | Homo sapiens | 11 | ALA5113456 | single protein format | Scientific Literature | |
4. | ALA5117109 | B | Inhibition of human eNOS using L-arginine as substrate assessed as reduction in NO production in the presence of NADPH by NO-hemoglobin capture assay | Homo sapiens | 11 | ALA5113456 | single protein format | Scientific Literature | |
5. | ALA5117110 | B | Selectivity index, ratio of Ki for inhibition of human nNOS to Ki for inhibition of rat nNOS using L-arginine as substrate assessed as reduction in NO production in the presence of NADPH by NO-hemoglobin capture assay | 11 | ALA5113456 | assay format | Scientific Literature | ||
6. | ALA5117111 | B | Selectivity index, ratio of Ki for inhibition of human nNOS to Ki for inhibition of human iNOS using L-arginine as substrate assessed as reduction in NO production in the presence of NADPH by NO-hemoglobin capture assay | Homo sapiens | 11 | ALA5113456 | protein format | Scientific Literature | |
7. | ALA5117112 | B | Selectivity index, ratio of Ki for inhibition of human nNOS to Ki for inhibition of human eNOS using L-arginine as substrate assessed as reduction in NO production in the presence of NADPH by NO-hemoglobin capture assay | Homo sapiens | 11 | ALA5113456 | assay format | Scientific Literature | |
8. | ALA5117113 | A | Effective permeability of compound in PBS buffer at pH 7.4 at 200 uM incubated for 17 hrs by PAMPA-BBB assay | 16 | ALA5113456 | assay format | Scientific Literature |