| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5130462 | B | Inhibition of STS in human T47D cells using [3H]E1S as substrate measured after 24 hrs by HPLC analysis | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA5130463 | B | Irreversible inhibition of STS in human T47D cells using [3H]E1S as substrate measured after 24 hrs by HPLC analysis | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 3. | ALA5130464 | B | Inhibition of human placental cytosolic fraction 17beta-HSD1 at 1 uM using [3H]-E1 as substrate measured after 10 mins in presence of NADH by HPLC method | Homo sapiens | 20 | subcellular format | Scientific Literature | ||
| 4. | ALA5130465 | A | Metabolic stability in human liver S9 fraction assessed as half life at 1 uM in presence of NADPH measured upto 60 min by LC-MS/MS analysis | Homo sapiens | 21 | subcellular format | Scientific Literature | ||
| 5. | ALA5130466 | A | Metabolic stability in mouse liver S9 fraction assessed as half life at 1 uM in presence of NADPH measured upto 60 min by LC-MS/MS analysis | Mus musculus | 21 | subcellular format | Scientific Literature | ||
| 6. | ALA5130467 | A | Metabolic stability in human liver S9 fraction assessed as intrinsic clearance at 1 uM in presence of NADPH measured upto 60 min by LC-MS/MS analysis | Homo sapiens | 21 | subcellular format | Scientific Literature | ||
| 7. | ALA5130468 | A | Metabolic stability in mouse liver S9 fraction assessed as intrinsic clearance at 1 uM in presence of NADPH measured upto 60 min by LC-MS/MS analysis | Mus musculus | 21 | subcellular format | Scientific Literature | ||
| 8. | ALA5130473 | B | Relative binding affinity to human recombinant ERalpha measured for 1 hrs by fluorescence based competitor assay relative to control | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 9. | ALA5130474 | T | Cytotoxicity against human HEK293 cells assessed as cell growth inhibition at 20 uM measured at 48 hrs bt MTT assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA5130475 | P | Stability of compound in phosphate buffer measured after 24 hrs by LC-MS/MS analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA5130476 | A | Stability in human T47D cells cultured in DMEM medium measured after 24 hrs by LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5130478 | A | Prodrug conversion in phosphate buffer assessed as 5-(4-Hydroxyphenyl)-N-methyl-N-(o-tolyl)furan-2-carboxamide formation by LC-MS/MS analysis | 1 | assay format | Scientific Literature | |||
| 13. | ALA5130479 | B | Inhibition of human placental cytosolic fraction 17beta-HSD1 at 50 nM using [3H]-E1 as substrate in presence of NADH measured after 6.5 hrs by LC-MS/MS method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA5130482 | A | Prodrug conversion in human T47D cells assessed as 5-(4-Hydroxyphenyl)-N-methyl-N-(o-tolyl)furan-2-carboxamide formation by LC-MS/MS analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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