| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5106374 | B | Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysis | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 2. | ALA5106375 | B | Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysis | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 3. | ALA5106376 | B | Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysis | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 4. | ALA5106377 | B | Inhibition of N-terminal GST-tagged PDGFRbeta (unknown origin) (557 to 1106 residues) measured by spectrophotometric analysis | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 5. | ALA5106378 | B | Inhibition of His-Glu tagged recombinant human KIT Q694-T753 deletion mutant (565 to 935 residues) measured by spectrophotometric analysis | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 6. | ALA5106379 | B | Inhibition of VEGFR2 (unknown origin) | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 7. | ALA5106380 | F | Antiproliferative activity against CSF1-treated mouse NFS-60 cells measured after 72 hrs by resazurin method | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 8. | ALA5106381 | B | Ratio IC50 for inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) over inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA5106382 | B | Ratio IC50 for inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) over inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA5106383 | B | Ratio IC50 for inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) over inhibition of N-terminal GST-tagged PDGFRbeta (unknown origin) (557 to 1106 residues) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA5106384 | B | Ratio IC50 for inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) over inhibition of VEGFR2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA5106385 | B | Ratio IC50 for inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) over inhibition of His-Glu tagged recombinant human KIT Q694-T753 deletion mutant (565 to 935 residues) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA5106386 | B | Inhibition of CSF1R in CSF1-stimulated human THP-1 cells assessed as inhibition of CSF1R phosphorylation measured by ELISA assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA5106387 | F | Inhibition of RANKL-induced human osteoclast precursor cells differentiation in presence of human CSF1 and measured by tartrate-resistant acid phosphatase activity assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA5106388 | A | Plasma concentration in DBA/1 mouse at 7.5 mg/kg, po administered once daily for 6 days and measured at 2 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA5106389 | A | Plasma concentration in DBA/1 mouse at 7.5 mg/kg, po administered once daily for 6 days and measured at 4 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA5106390 | A | Plasma concentration in DBA/1 mouse at 7.5 mg/kg, po administered once daily for 6 days and measured at 6 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA5106391 | A | Plasma concentration in DBA/1 mouse at 7.5 mg/kg, po administered once daily for 6 days and measured at 8 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA5106392 | A | Plasma concentration in DBA/1 mouse at 7.5 mg/kg, po administered once daily for 6 days and measured at 12 hrs | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA5106393 | A | Plasma concentration in DBA/1 mouse at 7.5 mg/kg, po administered once daily for 6 days and measured at 18 hrs | Mus musculus | 2 | organism-based format | Scientific Literature |
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