# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5130015 | B | Antagonist activity at human TLR9 expressed in HEK-blue hTLR9 cells assessed as inhibition of CpGB-induced NFkappaB activation preincubated with compound for 1 hrs followed by CpGB addition and measured next day by SEAP-based spectrophotometry assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
2. | ALA5130017 | B | Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation preincubated with compound for 1 hrs followed by CL264 addition and measured next day by SEAP-based spectrophotometry assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
3. | ALA5130033 | T | Cytotoxicity against human PBMCs assessed as reduction in cell viability measured upto 20 uM after overnight incubation by PI staining based flow cytometer analysis | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
4. | ALA5130034 | T | Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured upto 20 uM after overnight incubation by PI staining based flow cytometer analysis | Homo sapiens | 10 | cell-based format | Scientific Literature |