# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5152154 | T | Cytotoxicity against chick embryo fibroblast cells assessed as reduction in cell growth incubated for 48 hrs by CCK-8 assay | Gallus gallus | 6 | ALA5150010 | cell-based format | Scientific Literature | |
2. | ALA5152168 | B | Inhibition of Influenza A virus A/PR/8/1934 (H1N1) neuraminidase using 2(4-methylurnbellifery1)-a-u-acetyl neuraminic acid sodium salt hydrate (4-MUNANA) as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based microplate reader analysis | Influenza A virus | 27 | ALA5150010 | single protein format | Scientific Literature | |
3. | ALA5152169 | B | Inhibition of Influenza A virus A/Goose/Guangdong/SH7/2013 (H5N1) neuraminidase using 2(4-methylurnbellifery1)-a-u-acetyl neuraminic acid sodium salt hydrate (4-MUNANA) as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based microplate reader method | Influenza A virus | 27 | ALA5150010 | assay format | Scientific Literature | |
4. | ALA5152170 | B | Inhibition of Influenza A virus A/Goose/Jiangsu/1306/2014 (H5N8) neuraminidase using using 2(4-methylurnbellifery1)-a-u-acetyl neuraminic acid sodium salt hydrate (4-MUNANA) as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based microplate reader method | Influenza A virus | 27 | ALA5150010 | assay format | Scientific Literature | |
5. | ALA5152171 | B | Inhibition of Influenza A virus A/Babol/36/2005 (H3N2) neuraminidase using using 2(4-methylurnbellifery1)-a-u-acetyl neuraminic acid sodium salt hydrate (4-MUNANA) as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based microplate reader method | Influenza A virus | 27 | ALA5150010 | assay format | Scientific Literature | |
6. | ALA5152175 | B | Inhibition of Influenza A virus (A/California/07/2009 (H1N1)) neuraminidase H275Y mutant using 2(4-methylurnbellifery1)-a-u-acetyl neuraminic acid sodium salt hydrate (4-MUNANA) as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based microplate reader method | Influenza A virus | 7 | ALA5150010 | assay format | Scientific Literature | |
7. | ALA5152176 | B | Inhibition of Influenza A virus A/Anhui/1/2005 (H5N1) Neuraminidase H274Y mutant using 2(4-methylurnbellifery1)-a-u-acetyl neuraminic acid sodium salt hydrate (4-MUNANA) as substrate preincubated for 10 mins followed by substrate addition and measured after 40 mins by fluorescence based microplate reader method | Influenza A virus | 7 | ALA5150010 | assay format | Scientific Literature | |
8. | ALA5152177 | B | Potency index, ratio of OSC IC50 to test compound IC50 for inhibition of Influenza A virus (A/California/07/2009 (H1N1)) neuraminidase H275Y mutant | Influenza A virus | 4 | ALA5150010 | assay format | Scientific Literature | |
9. | ALA5152178 | B | Potency index, ratio of OSC IC50 to test compound IC50 for inhibition of Influenza A virus A/Anhui/1/2005 (H5N1) Neuraminidase H274Y mutant | Influenza A virus | 4 | ALA5150010 | assay format | Scientific Literature | |
10. | ALA5152179 | F | Antiviral activity against Influenza A virus A/Goose/Guangdong/SH7/2013 (H5N1) infected in chick embryo fibroblast assessed as reduction in virus-induced cytopathic effect measured for 48 hrs by CCK-8 assay | Influenza A virus | 6 | ALA5150010 | organism-based format | Scientific Literature | |
11. | ALA5152180 | F | Antiviral activity against Influenza A virus A/Goose/Jiangsu/1306/2014 (H5N8) infected in chick embryo fibroblast assessed as reduction in virus-induced cytopathic effect measured for 48 hrs by CCK-8 assay | Influenza A virus | 6 | ALA5150010 | organism-based format | Scientific Literature | |
12. | ALA5152181 | T | Selectivity index, ratio of CC50 for cytotoxicity against CEF cells to EC50 for antiviral activity against Influenza A virus A/Goose/Guangdong/SH7/2013 (H5N1) infected in chick embryo fibroblast | 6 | ALA5150010 | cell-based format | Scientific Literature | ||
13. | ALA5152182 | T | Selectivity index, ratio of CC50 for cytotoxicity against CEF cells to EC50 for antiviral activity against Influenza A virus A/Goose/Jiangsu/1306/2014 (H5N8) infected in chick embryo fibroblast | 6 | ALA5150010 | cell-based format | Scientific Literature | ||
14. | ALA5152184 | F | Antiviral activity against Influenza A virus A/PR/8/34 (H1N1) infected in dog MDCK cells assessed as inhibition of plaque formation incubated for 2 days by plaque reduction assay | Influenza A virus | 6 | ALA5150010 | organism-based format | Scientific Literature | |
15. | ALA5152185 | F | Antiviral activity against Influenza A virus A/Wisconsin/67/05 (H3N2) infected in dog MDCK cells assessed as inhibition of plaque formation incubated for 2 days by plaque reduction assay | Influenza A virus | 6 | ALA5150010 | organism-based format | Scientific Literature | |
16. | ALA5152186 | T | Cytotoxicity against dog MDCK cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay | Canis lupus familiaris | 6 | ALA5150010 | cell-based format | Scientific Literature |