#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5130015	B	Antagonist activity at human TLR9 expressed in HEK-blue hTLR9 cells assessed as inhibition of CpGB-induced NFkappaB activation preincubated with compound for 1 hrs followed by CpGB addition and measured next day by SEAP-based spectrophotometry assay	Homo sapiens	40		cell-based format	Scientific Literature
2.	ALA5130017	B	Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation preincubated with compound for 1 hrs followed by CL264 addition and measured next day by SEAP-based spectrophotometry assay	Homo sapiens	40		cell-based format	Scientific Literature
3.	ALA5130022	B	Antagonist activity at human TLR8 expressed in HEK-blue hTLR8 cells assessed as inhibition of CL075-induced NFkappaB activation preincubated with compound for 1 hrs followed by CL075 addition and measured next day by SEAP-based spectrophotometry assay	Homo sapiens	2		cell-based format	Scientific Literature
4.	ALA5130024	P	1-Octanol/phosphate buffer partition coefficient, logD of the compound measured after 4.5 hrs by HPLC-UV analysis		6		small-molecule physicochemical format	Scientific Literature
5.	ALA5130025	P	Kinetic aqueous solubility of the compound in phosphate buffer at 500 uM at pH 7.4 measured after 24 hrs by HPLC-UV spectrophotometer analysis		10		small-molecule physicochemical format	Scientific Literature
6.	ALA5130026	A	Stability in human plasma assessed as parent compound remaining at 1 uM measured after 2 hrs by LC-MS/MS analysis	Homo sapiens	10		cell-free format	Scientific Literature
7.	ALA5130027	A	Stability in mouse plasma assessed as parent compound remaining at 1 uM measured after 2 hrs by LC-MS/MS analysis	Mus musculus	10		cell-free format	Scientific Literature
8.	ALA5130028	A	Metabolic stability in human liver microsomes assessed as half life at 5 uM measured for 60 mins by LC-MS/MS analysis	Homo sapiens	9		microsome format	Scientific Literature
9.	ALA5130029	A	Metabolic stability in mouse liver microsomes assessed as half life at 5 uM measured for 60 mins by LC-MS/MS analysis	Mus musculus	9		microsome format	Scientific Literature
10.	ALA5130033	T	Cytotoxicity against human PBMCs assessed as reduction in cell viability measured upto 20 uM after overnight incubation by PI staining based flow cytometer analysis	Homo sapiens	10		cell-based format	Scientific Literature
11.	ALA5130034	T	Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured upto 20 uM after overnight incubation by PI staining based flow cytometer analysis	Homo sapiens	10		cell-based format	Scientific Literature