| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5166084 | B | Binding affinity to wild type human partial length JAK3 (I781 to S1124 residues) expressed in mammalian expression system by Kinomescan binding assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA5166085 | B | Inhibition of ERK5 (unknown origin) using K-5FAM-LVEPLTPSGEAPNQ-COOH as substrate incubated for 2 hrs in presence of ATP by IMAP-FP assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 3. | ALA5166086 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 17 | microsome format | Scientific Literature | ||
| 4. | ALA5166088 | A | Apparent permeability of the compound across apical to basolateral side in human Caco-2 cells | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 5. | ALA5166089 | A | Efflux ratio of apparent permeability in human Caco-2 cells | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 6. | ALA5166090 | B | Inhibition of ERK5 phosphorylation in human HeLa cells incubated for 1 hr by Western blot densitometry analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA5166091 | A | Clearance in mouse at 10 mg/kg, po or 10 mg/kg, iv measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA5166092 | A | Volume of distribution in mouse at 10 mg/kg, po or 10 mg/kg, iv measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA5166093 | A | Half life in mouse at 10 mg/kg, po or 10 mg/kg, iv measured upto 60 mins by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA5166094 | A | Oral bioavailability in mouse at 10 mg/kg measured upto 60 min by LC-MS analysis | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA5166095 | B | Inhibition of P38 (unknown origin) | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 12. | ALA5166096 | B | Inhibition of MAP3K (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA5166097 | B | Inhibition of ERK1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5166098 | B | Inhibition of ERK2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA5166099 | B | Inhibition of JNK1 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA5166100 | B | Inhibition of JNK2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5166101 | B | Inhibition of JNK3 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA5166102 | B | Inhibition of BRD4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5166103 | B | Binding affinity to wild-type human partial length CSF1R (I564 to S939 residues) expressed in bacterial expression system by Kinomescan assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA5166104 | B | Binding affinity to wild-type human partial length DCLK1 (L270 to A662 residues) expressed in mammalian expression system by Kinomescan assay | Homo sapiens | 1 | assay format | Scientific Literature |
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