# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5127374 | B | Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli at 10 uM using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Mus musculus | 5 | assay format | Scientific Literature | ||
2. | ALA5127387 | B | Inhibition of human recombinant Pim1 expressed in Escherichia coli at 10 uM using histone H1 as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 12 | assay format | Scientific Literature | ||
3. | ALA5127389 | B | Inhibition of human recombinant CK2 at 10 uM using RRRDDDSDDD peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting method | Homo sapiens | 22 | protein format | Scientific Literature | ||
4. | ALA5127391 | F | Neuroprotective activity against glutamate-induced cell death in mouse HT-22 cells treated for 24 hrs by MTS assay | Mus musculus | 41 | cell-based format | Scientific Literature | ||
5. | ALA5127392 | B | Induction of PI3K/mTor-dependent autophagy in human U2OS cells assessed as number of LC3 foci per cell at 10 uM measured after 4 hrs | Homo sapiens | 64 | cell-based format | Scientific Literature | ||
6. | ALA5127393 | B | Modulation of CLK1 pre-mRNA splicing in mouse HT-22 cells assessed as inclusion of CLK1 exon 4 by measuring change in threshold cycle at 10 uM measured after 4 hrs by real time PCR analysis | Mus musculus | 64 | cell-based format | Scientific Literature | ||
7. | ALA5127394 | B | Inhibition of DYRK1A in human SH-SY5Y overexpressing Tau4R cells assessed as phosphorylated Tau Thr212 residue level at 10 uM incubated for 6 hrs by western blot analysis relative to control | Homo sapiens | 64 | cell-based format | Scientific Literature | ||
8. | ALA5127395 | F | Antagonist activity at CP-55940-activated CB1 receptor (unknown origin) at 10 uM by beta-arrestin assay relative to control | Homo sapiens | 64 | assay format | Scientific Literature | ||
9. | ALA5127410 | T | Neurotoxicity against mouse HT-22 cells assessed as cell survival at 20 uM treated for 24 hrs by MTS assay | Mus musculus | 46 | cell-based format | Scientific Literature |