# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5167089 | F | Inhibition of cell proliferation in human MDA-MB-453 cells incubated for 72 hrs by Cell Titer-Glo luminescent assay | Homo sapiens | 22 | ALA5154909 | cell-based format | Scientific Literature | |
2. | ALA5167092 | B | Inhibition of N-terminal GST tagged FGFR4 (unknown origin) expressed in baculovirus infected sf21 insect cells incubated for 2 hrs by HTRF analysis | Homo sapiens | 23 | ALA5154909 | cell-based format | Scientific Literature | |
3. | ALA5167093 | F | Inhibition of cell proliferation in human Huh-7 cells incubated for 72 hrs by Cell Titer-Glo luminescent assay | Homo sapiens | 22 | ALA5154909 | cell-based format | Scientific Literature | |
4. | ALA5167095 | B | Time-dependent inhibition of FGFR4 (unknown origin) at 8 nM preincubated for 45 mins followed by substrate and ATP addition by HTRF analysis | Homo sapiens | 1 | ALA5154909 | single protein format | Scientific Literature | |
5. | ALA5167097 | B | Inhibition of BODIPY-FL-labeled 3-(3-(4-(3-acrylamido-4-((3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl)amino)phenyl)piperazin-1-yl)-3-oxopropyl)-5,5-difluoro-7,9-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide probe binding to recombinant FGFR4 (unknown origin) preincubated for 2 hrs followed by probe treatment for 2 hrs by SDS/PAGE and fluorescent gel scanning analysis | Homo sapiens | 4 | ALA5154909 | single protein format | Scientific Literature | |
6. | ALA5167098 | B | Inhibition of FGFR4 (unknown origin) at 1 uM by Z'-LYTE assay relative to control | Homo sapiens | 2 | ALA5154909 | single protein format | Scientific Literature | |
7. | ALA5167099 | B | Inhibition of FGFR1 (unknown origin) by Z'-LYTE assay | Homo sapiens | 1 | ALA5154909 | single protein format | Scientific Literature | |
8. | ALA5167100 | B | Inhibition of FGFR2 (unknown origin) by Z'-LYTE assay | Homo sapiens | 1 | ALA5154909 | single protein format | Scientific Literature | |
9. | ALA5167101 | B | Inhibition of CSF1R (unknown origin) at upto 10 uM by Z'-LYTE assay | Homo sapiens | 1 | ALA5154909 | single protein format | Scientific Literature | |
10. | ALA5167105 | B | Inhibition of FGF19 induced FGFR4 signalling in human Huh-7 cells assessed as inhibition of FRS2alpha phosphorylation at Y436 residue at 30 nM incubated for 1 hr followed by FGF19 stimulation for 10 mins by Western blot analysis | Homo sapiens | 2 | ALA5154909 | cell-based format | Scientific Literature | |
11. | ALA5167107 | B | Inhibition of FGF19 induced FGFR4 signalling in human Huh-7 cells assessed as inhibition of AKT phosphorylation at S473 residue incubated for 1 hr followed by FGF19 stimulation for 10 mins by Western blot analysis | Homo sapiens | 2 | ALA5154909 | cell-based format | Scientific Literature | |
12. | ALA5167108 | B | Inhibition of FGF19 induced FGFR4 signalling in human Huh-7 cells assessed as inhibition of ERK phosphorylation at T202/Y204 residues incubated for 1 hr followed by FGF19 stimulation for 10 mins by Western blot analysis | Homo sapiens | 2 | ALA5154909 | cell-based format | Scientific Literature | |
13. | ALA5167126 | B | Inhibition of ABL1 (unknown origin) at 1 uM in presence of ATP by Z'-LYTE assay relative to control | Homo sapiens | 2 | ALA5154909 | single protein format | Scientific Literature | |
14. | ALA5167130 | B | Inhibition of AKT1 (unknown origin) at 1 uM in presence of ATP by Z'-LYTE assay relative to control | Homo sapiens | 2 | ALA5154909 | single protein format | Scientific Literature | |
15. | ALA5167131 | B | Inhibition of AURKA (unknown origin) at 1 uM in presence of ATP by Z'-LYTE assay relative to control | Homo sapiens | 2 | ALA5154909 | single protein format | Scientific Literature | |
16. | ALA5167132 | B | Inhibition of BRAF (unknown origin) at 1 uM by LanthaScreen assay relative to control | Homo sapiens | 2 | ALA5154909 | single protein format | Scientific Literature | |
17. | ALA5167133 | B | Inhibition of TTK (unknown origin) at 1 uM by LanthaScreen assay relative to control | Homo sapiens | 2 | ALA5154909 | single protein format | Scientific Literature | |
18. | ALA5167134 | B | Inhibition of BTK (unknown origin) at 1 uM in presence of ATP by Z'-LYTE assay relative to control | Homo sapiens | 2 | ALA5154909 | single protein format | Scientific Literature | |
19. | ALA5167135 | B | Inhibition of CDK2/cyclin A (unknown origin) at 1 uM in presence of ATP by Z'-LYTE assay relative to control | Homo sapiens | 2 | ALA5154909 | protein complex format | Scientific Literature | |
20. | ALA5167136 | B | Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) at 1 uM in presence of ATP by Z'-LYTE assay relative to control | Homo sapiens | 2 | ALA5154909 | protein complex format | Scientific Literature |