# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5100119 | Binding | Binding affinity to HER2 in HER-positive human SK-BR-3 cells assessed as increase in fluorescence intensity at 25 uM by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 4 | ALA5096235 | cell-based format | Scientific Literature | |
2. | ALA5100120 | Binding | Binding affinity to HER2 in HER-negative human MDA-MB-231 cells assessed as increase in fluorescence intensity at 25 uM by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 2 | ALA5096235 | cell-based format | Scientific Literature | |
3. | ALA5100121 | ADME | Drug uptake in tumor of nude mouse xenografted with HER2-positive human SK-BR-3 cells assessed as increase in fluorescence intensity at 25 uM, iv measured after 2 hrs by IVIS spectrum in vivo imaging analysis | Mus musculus | 2 | ALA5096235 | organism-based format | Scientific Literature |