# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5166901 | B | Inhibition of human Notum (S81 to T451 residues) Cys330Ser mutant expressed in HEK293S cells using OPTS as substrate incubated for 40 mins by fluorescence based assay | Homo sapiens | 42 | ALA5154906 | cell-based format | Scientific Literature | |
2. | ALA5166903 | P | Aqueous solubility of compound in PBS at pH 7.4 | 7 | ALA5154906 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA5166904 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 7 | ALA5154906 | microsome format | Scientific Literature | |
4. | ALA5166905 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 7 | ALA5154906 | microsome format | Scientific Literature | |
5. | ALA5166906 | A | Apparent permeability across apical to basolateral side in MDCK-MDR1 cells | Canis lupus familiaris | 7 | ALA5154906 | cell-based format | Scientific Literature | |
6. | ALA5166907 | A | Apparent permeability across basolateral to apical side in MDCK-MDR1 cells | Canis lupus familiaris | 7 | ALA5154906 | cell-based format | Scientific Literature | |
7. | ALA5166908 | A | Efflux ratio of apparent permeability from apical to basolateral side over basolateral to apical side in MDCK-MDR1 cells | Canis lupus familiaris | 7 | ALA5154906 | cell-based format | Scientific Literature |