| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5161313 | B | Inhibition of N-terminal 6His-tagged FGFR4 (unknown orgin) (445 to 753 residues) expressed in Rosetta (NEB) cells using Tyr 04 peptide as substrate incubated for 1 hr in presence of 150 uM ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 2. | ALA5161314 | B | Inhibition of FGFR1 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 25 uM ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 3. | ALA5161315 | B | Inhibition of FGFR2 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 5 uM ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 4. | ALA5161316 | B | Inhibition of FGFR3 (unknown orgin) using Tyr 04 peptide as substrate incubated for 1 hr in presence of 75 uM ATP by FRET based Z'-LYTE assay | Homo sapiens | 32 | single protein format | Scientific Literature | ||
| 5. | ALA5161317 | F | Antiproliferative activity against mouse BAF3 cells expressing wild-type FGFR4 assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 6. | ALA5161318 | F | Antiproliferative activity against human MDA-MB-453 cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 7. | ALA5161319 | F | Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 8. | ALA5161320 | F | Antiproliferative activity against human NCI-H1299 cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 9. | ALA5161321 | B | Inhibition of N-terminal 6His-tagged FGFR4 (unknown orgin) (445 to 753 residues) expressed in Rosetta (NEB) cells using poly(Glu, Tyr) 4:1 peptide as substrate incubated for 30 mins in presence of 50 uM ATP by ADP-Glo fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA5161322 | B | Inhibition of FGFR4 V550L mutant (unknown orgin) using poly(Glu, Tyr) 4:1 peptide as substrate incubated for 30 mins in presence of 50 uM ATP by ADP-Glo fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA5161323 | B | Inhibition of FGFR4 V550M mutant (unknown orgin) using poly(Glu, Tyr) 4:1 peptide as substrate incubated for 30 mins in presence of 50 uM ATP by ADP-Glo fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 12. | ALA5161324 | B | Inhibition of FGFR4 C552S mutant (unknown orgin) using poly(Glu, Tyr) 4:1 peptide as substrate incubated for 30 mins in presence of 50 uM ATP by ADP-Glo fluorescence assay | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 13. | ALA5161325 | F | Antiproliferative activity against mouse BAF3 cells expressing FGFR4 V550L mutant assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA5161326 | F | Antiproliferative activity against mouse BAF3 cells expressing FGFR4 V550M mutant assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA5161327 | F | Antiproliferative activity against human JHH7 cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA5161328 | F | Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth incubated for 5 days by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA5161329 | F | Antiproliferative activity against mouse BAF3 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA5161330 | B | Inhibition of wild type FGFR4 phosphorylation in mouse BAF3 cells at 30 nM incubated for 6 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5161331 | B | Inhibition of wild type FGFR4 phosphorylation in mouse BAF3 cells assessed as reduction in FRS2 level at 3 to 90 nM incubated for 6 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5161332 | B | Inhibition of wild type FGFR4 phosphorylation in mouse BAF3 cells assessed as reduction in MAPK level at 3 to 90 nM incubated for 6 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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