# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5147523 | F | Cytotoxicity against human A375 cells after 48 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
2. | ALA5147524 | F | Cytotoxicity against human OE19 cells after 48 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA5147525 | F | Cytotoxicity against human OE19 cells after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA5147526 | F | Cytotoxicity against human HT-1080 cells after 48 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
5. | ALA5147527 | F | Cytotoxicity against human H1299 cells after 48 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
6. | ALA5147528 | F | Induction of apoptosis in human A375 cells assessed as viable cells at 10 uM after 48 hrs by annexin-v and PI staining based flow cytometry analysis (Rvb = 93.63 +/- 1.37%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA5147529 | F | Induction of apoptosis in human A375 cells assessed as late apoptotic cells at 10 uM after 48 hrs by annexin-v and PI staining based flow cytometry analysis (Rvb = 1.83 +/- 0.41%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA5147530 | F | Induction of apoptosis in human A375 cells assessed as necrotic cells at 10 uM after 48 hrs by annexin-v and PI staining based flow cytometry analysis (Rvb = 1.17 +/- 0.41%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA5147531 | F | Induction of apoptosis in human A375 cells at 5 uM after 48 hrs by annexin-v and PI staining based flow cytometry analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA5147537 | F | Induction of cell cycle arrest in human A375 assessed as number of cells at G1 phase at 10 uM after 48 hrs by flow cytometry (Rvb = 83.5 +/- 1.87 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA5147538 | F | Induction of cell cycle arrest in human A375 assessed as number of cells at S phase at 10 uM after 48 hrs by flow cytometry (Rvb = 5.17 +/- 1.86 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
12. | ALA5147539 | F | Induction of cell cycle arrest in human A375 assessed as number of cells at G2/M phase at 10 uM after 48 hrs by flow cytometry (Rvb = 5.17 +/- 0.75 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA5147540 | F | Effect on reactive oxygen production in human A375 cells assessed as decrease in peroxide level at 10 uM after 48 hrs by DCFH2-DA staining based spectrophotometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
14. | ALA5147541 | F | Effect on reactive oxygen production in human A375 cells assessed as superoxide anion level at 5 to 10 uM after 48 hrs by DHE staining based spectrophotometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
15. | ALA5147542 | B | Inhibition of MMP9 in human HT-1080 cells at 10 uM by gelatin zymography | Homo sapiens | 7 | cell-based format | Scientific Literature |