# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5165090 | B | Binding affinity towards His-tagged recombinant human PD-L1 measured by MicroScale Thermophoresis (MST) assay | Homo sapiens | 39 | ALA5154872 | single protein format | Scientific Literature | |
2. | ALA5165091 | B | Binding affinity towards His-tagged recombinant human PD-L1 measured by MST dimerization binding assay | Homo sapiens | 6 | ALA5154872 | single protein format | Scientific Literature | |
3. | ALA5165092 | B | Inhibition of human PD-1/PD-L1 interaction in CHO-K1 cells transfected with PD-1-YFP/SHP-2-CFP and measured by FRET assay | Homo sapiens | 12 | ALA5154872 | cell-based format | Scientific Literature | |
4. | ALA5165093 | B | Binding affinity towards His-tagged recombinant human PD-L1 measured by Isothermal Titration Calorimetry (ITC) assay | Homo sapiens | 1 | ALA5154872 | single protein format | Scientific Literature | |
5. | ALA5165094 | F | Reactivation of mouse CTLL-2 cells pretreated with human PD-L1 assessed as increase in cell proliferation and measured by flow cytometry assay | Mus musculus | 5 | ALA5154872 | cell-based format | Scientific Literature | |
6. | ALA5165095 | P | Solubility in PBS at pH 7.4 | 5 | ALA5154872 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA5165096 | P | 1-Octanol/phosphate buffered-saline distribution coefficient, logD of compound at pH 7.4 measured after 2 hrs by LC-MS analysis | 5 | ALA5154872 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA5165097 | A | Stability in CD-1 mouse plasma assessed as half-ife at 10 uM | Mus musculus | 5 | ALA5154872 | cell-free format | Scientific Literature |