| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5106439 | B | Inhibition of N-terminal His6-tagged recombinant human CSF1R (542 to 919 residues) measured by spectrophotometric analysis | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 2. | ALA5106440 | B | Inhibition of His-tagged recombinant human FLT3 (564 to 958 residues) measured by spectrophotometric analysis | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 3. | ALA5106441 | B | Inhibition of N-terminal GST-tagged PDGFRalpha (unknown origin) (550 to 1089 residues) measured by spectrophotometric analysis | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 4. | ALA5106442 | B | Inhibition of N-terminal GST-tagged PDGFRbeta (unknown origin) (557 to 1106 residues) measured by spectrophotometric analysis | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 5. | ALA5106443 | B | Inhibition of His-Glu tagged recombinant human KIT Q694-T753 deletion mutant (565 to 935 residues) measured by spectrophotometric analysis | Homo sapiens | 25 | assay format | Scientific Literature | ||
| 6. | ALA5106444 | B | Inhibition of VEGFR2 (unknown origin) measured by spectrophotometric analysis | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 7. | ALA5106445 | B | Inhibition of N-terminal His-Glu-TEV-tagged MET (unknown origin) (1050 to 1360 residues) measured by spectrophotometric analysis | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 8. | ALA5106446 | F | Antiproliferative activity against CSF1-treated mouse NFS-60 cells measured after 72 hrs by resazurin method | Mus musculus | 25 | cell-based format | Scientific Literature | ||
| 9. | ALA5106447 | F | Inhibition of RANKL-induced human osteoclast precursor cells differentiation in presence of human M-CSF and measured by tartrate-resistant acid phosphatase activity assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA5106448 | A | Plasma concentration in DBA/1 mouse at 15 mg/kg, po administered once daily for 6 days and measured at 2 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA5106449 | A | Plasma concentration in DBA/1 mouse at 15 mg/kg, po administered once daily for 6 days and measured at 4 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA5106450 | A | Plasma concentration in DBA/1 mouse at 15 mg/kg, po administered once daily for 6 days and measured at 6 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA5106451 | A | Plasma concentration in DBA/1 mouse at 15 mg/kg, po administered once daily for 6 days and measured at 8 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA5106452 | A | Plasma concentration in DBA/1 mouse at 15 mg/kg, po administered once daily for 6 days and measured at 12 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5106453 | A | Plasma concentration in DBA/1 mouse at 15 mg/kg, po administered once daily for 6 days and measured at 18 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5106454 | A | Plasma concentration in DBA/1 mouse at 15 mg/kg, po administered once daily for 6 days and measured at 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5106455 | F | In vivo inhibition of CSF1R in CSF1-stimulated DBA/1 mouse assessed as modulation of cFOS mRNA at 15 mg/kg, po administered once daily for 6 days followed by CSF1 administration through intravenously and measured at 2 hrs by RT-PCR method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA5106456 | F | In vivo inhibition of CSF1R in CSF1-stimulated DBA/1 mouse assessed as modulation of cFOS mRNA at 15 mg/kg, po administered once daily for 6 days followed by CSF1 administration through intravenously and measured at 4 hrs by RT-PCR method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA5106457 | F | In vivo inhibition of CSF1R in CSF1-stimulated DBA/1 mouse assessed as modulation of cFOS mRNA at 15 mg/kg, po administered once daily for 6 days followed by CSF1 administration through intravenously and measured at 6 hrs by RT-PCR method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA5106458 | F | In vivo inhibition of CSF1R in CSF1-stimulated DBA/1 mouse assessed as modulation of cFOS mRNA at 15 mg/kg, po administered once daily for 6 days followed by CSF1 administration through intravenously and measured at 8 hrs by RT-PCR method | Mus musculus | 1 | organism-based format | Scientific Literature |
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