#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5141668	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation at 2.5 to 10 uM incubated for 48 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
2.	ALA5141671	B	Binding affinity to N-terminal GST-tagged human NSD2 PWWP1 domain (208 to 369 residues) expressed in Escherichia coli BL2I (DE3) cells assessed as dissociation constant by isothermal titration calorimetry assay	Homo sapiens	3	ALA5137075	cell-based format	Scientific Literature
3.	ALA5141673	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation incubated for 48 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
4.	ALA5141674	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation by measuring maximal efficacy at 0.5 to 10 uM incubated for 48 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
5.	ALA5141675	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
6.	ALA5141676	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM incubated for 48 hrs followed by CRBN E3 ligase ligand, pomalidomide addition at 10 uM for last 6 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
7.	ALA5141677	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM incubated for 48 hrs followed by UNC693 addition at 5 uM for last 6 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
8.	ALA5141678	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM incubated for 48 hrs followed by proteasome inhibitor, MG132 addition at 5 uM for last 6 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
9.	ALA5141679	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM incubated for 48 hrs followed by neddylation inhibitor, MLN492 addition at 10 uM for last 6 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
10.	ALA5141680	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM incubated for 72 hrs followed by compound washout and measured upto 48 hrs post washout by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
11.	ALA5141681	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in human KMS-11 cells assessed as induction of NSD2 degradation 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	4	ALA5137075	cell-based format	Scientific Literature
12.	ALA5141682	B	Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in human NCI-H929 cells assessed as induction of NSD2 degradation 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	4	ALA5137075	cell-based format	Scientific Literature
13.	ALA5141683	B	PROTAC activity at CRBN/GSPT1 in human KMS-11 cells assessed as induction of GSPT1 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	3	ALA5137075	cell-based format	Scientific Literature
14.	ALA5141684	B	PROTAC activity at CRBN/GSPT1 in human NCI-H929 cells assessed as induction of GSPT1 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	3	ALA5137075	cell-based format	Scientific Literature
15.	ALA5141685	B	Protac activity at CRBN/IKZF1 in human KMS-11 cells assessed as induction of IKZF1 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	4	ALA5137075	cell-based format	Scientific Literature
16.	ALA5141686	B	Protac activity at CRBN/IKZF1 in human NCI-H929 cells assessed as induction of IKZF1 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	4	ALA5137075	cell-based format	Scientific Literature
17.	ALA5141687	B	Protac activity at CRBN/IKZF3 in human KMS-11 cells assessed as induction of IKZF3 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	4	ALA5137075	cell-based format	Scientific Literature
18.	ALA5141688	B	Protac activity at CRBN/IKZF3 in human NCI-H929 cells assessed as induction of IKZF3 degradation at 2.5 uM incubated for 72 hrs by Western blot analysis	Homo sapiens	4	ALA5137075	cell-based format	Scientific Literature
19.	ALA5141693	B	Protac activity at CRBN/IKZF3 in HEK293FT cells assessed as induction of IKZF3 degradation at 5 uM pretreated with proteosome inhibitor MLN9708 for 2 hrs followed by compound addition and measured after 6 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature
20.	ALA5141694	B	Protac activity at CRBN/IKZF3 in HEK293FT cells assessed as induction of IKZF3 degradation at 5 uM pretreated with neddylation inhibitor MLN4924 for 2 hrs followed by compound addition and measured after 6 hrs by Western blot analysis	Homo sapiens	1	ALA5137075	cell-based format	Scientific Literature