#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5155866	Binding	Activation of human IDE mediated insulin hydrolysis at 100 uM pre-incubated for 1 to 10 min followed by substrate addition by HPLC analysis	Homo sapiens	1	ALA5154655	single protein format	Scientific Literature
2.	ALA5155867	Binding	Activation of human recombinant IDE using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-trp as substrate incubated for 10 mins followed by substrate addition and measured after 20 mins by fluorescence spectrophotometer analysis	Homo sapiens	20	ALA5154655	single protein format	Scientific Literature
3.	ALA5155868	Binding	Activation of human recombinant IDE assessed as activation efficacy using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-trp as substrate at 100 uM incubated for 10 mins followed by substrate addition and measured after 20 mins by fluorescence spectrophotometer analysis relative to control	Homo sapiens	1	ALA5154655	single protein format	Scientific Literature
4.	ALA5155869	Binding	Activation of human recombinant IDE assessed as fold change in activation efficacy using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-trp as substrate at 100 uM incubated for 10 mins followed by substrate addition and measured after 20 mins by fluorescence spectrophotometer analysis	Homo sapiens	29	ALA5154655	single protein format	Scientific Literature
5.	ALA5155870	Physicochemical	Lipophilicity, logD of the compound in 1-octanol and phosphate buffer at pH 7.4 incubated for 2 hrs under shaking condition by LC-MS/MS analysis		2	ALA5154655	small-molecule physicochemical format	Scientific Literature
6.	ALA5155871	Physicochemical	Aqueous thermodynamic solubility of the compound in phosphate buffer/MeOH at pH 7.4 measured after 24 hrs by LC-MS/MS analysis		1	ALA5154655	small-molecule physicochemical format	Scientific Literature
7.	ALA5155872	ADME	Stability in rat plasma assessed as half life at 10 uM	Rattus norvegicus	1	ALA5154655	cell-free format	Scientific Literature
8.	ALA5155873	Functional	Inhibition of glucose induced insulin secretion in mouse MIN6 cells preincubated for 1 hr followed by glucose stimulation and measured after 1 hr by ELISA method	Mus musculus	1	ALA5154655	cell-based format	Scientific Literature
9.	ALA5155874	Functional	Inhibition of glucose induced insulin secretion in mouse MIN6 cells assessed as decrease in insulin content preincubated for 1 hr followed by glucose stimulation and measured after 1 hr by ELISA method	Mus musculus	1	ALA5154655	cell-based format	Scientific Literature