| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5141533 | A | Stability of the compound in rat plasma assessed as prodrug release at 100 ug/ml measured for 8 hrs by HPLC analysis | Rattus norvegicus | 1 | ALA5137072 | cell-free format | Scientific Literature | |
| 2. | ALA5141534 | A | Stability of the compound in rat plasma assessed as prodrug release at 100 ug/ml measured for 8 to 12 hrs by HPLC analysis | Rattus norvegicus | 1 | ALA5137072 | cell-free format | Scientific Literature | |
| 3. | ALA5141535 | A | Selectivity ratio of drug degradation in human A549 cells assessed as increase in red fluorescence to drug degradation in human HFL1 cells assessed as increase in red fluorescence | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 4. | ALA5141536 | A | Drug localization in mitochondria of human A549 cells measured after 4 hrs by Mito Tracker Green FM based confocal laser scanning microscopy analysis | Homo sapiens | 1 | ALA5137072 | mitochondrion format | Scientific Literature | |
| 5. | ALA5141537 | F | Synergistic antiproliferative activity against human A549 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of SAHA by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 6. | ALA5141538 | F | Synergistic antiproliferative activity against human HepG2 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of SAHA by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 7. | ALA5141539 | F | Synergistic antiproliferative activity against human HT-29 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of SAHA by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 8. | ALA5141540 | F | Synergistic antiproliferative activity against human MCF7 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of SAHA by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 9. | ALA5141541 | T | Synergistic antiproliferative activity against human HFL1 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of SAHA by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 10. | ALA5141542 | T | Synergistic antiproliferative activity against human L02 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of SAHA by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 11. | ALA5141543 | F | Synergistic antiproliferative activity against human A549 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of CDDO-Me by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 12. | ALA5141544 | F | Synergistic antiproliferative activity against human HepG2 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of CDDO-Me by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 13. | ALA5141545 | F | Synergistic antiproliferative activity against human HT-29 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of CDDO-Me by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 14. | ALA5141546 | F | Synergistic antiproliferative activity against human MCF7 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of CDDO-Me by MTT assay | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 15. | ALA5141547 | T | Synergistic antiproliferative activity against human HFL1 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of CDDO-Me by MTT assay | Homo sapiens | 2 | ALA5137072 | cell-based format | Scientific Literature | |
| 16. | ALA5141548 | T | Synergistic antiproliferative activity against human L02 cells at 2.5 to 12.5 uM measured after 72 hrs in presence of CDDO-Me by MTT assay | Homo sapiens | 2 | ALA5137072 | cell-based format | Scientific Literature | |
| 17. | ALA5141549 | F | Induction of necrosis in human A549 cells xenografted in BALB/c mouse at 12 umol/kg, iv administered for 20 days and measured every 3 days for 21 days by TUNEL assay | Homo sapiens | 1 | ALA5137072 | organism-based format | Scientific Literature | |
| 18. | ALA5141550 | F | Induction of apoptosis in human A549 cells xenografted in BALB/c mouse at 12 umol/kg, iv administered for 20 days and measured every 3 days for 21 days by TUNEL assay | Homo sapiens | 1 | ALA5137072 | organism-based format | Scientific Literature | |
| 19. | ALA5141551 | F | Induction of ROS accumulation in human A549 cells at 15 uM incubated for 2 hrs by DCFH2-DA staining based confocal microscopic analysis | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature | |
| 20. | ALA5141552 | F | Induction of mitochondrial membrane depolarization in human A549 cells at 15 uM incubated for 2 hrs by JC-1 staining based analysis | Homo sapiens | 1 | ALA5137072 | cell-based format | Scientific Literature |
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