| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5116773 | B | Inhibition of G9a (unknown origin) | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 2. | ALA5116774 | B | Inhibition of GLP (unknown origin) | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 3. | ALA5116775 | B | Selectivity index, ratio of IC50 for inhibition of GLP (unknown origin) to IC50 for inhibition of G9a (unknown origin) | Homo sapiens | 16 | assay format | Scientific Literature | ||
| 4. | ALA5116776 | B | Inhibition of SETDB1 (unknown origin) at upto 10 uM | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 5. | ALA5116777 | B | Inhibition of SUV39H1 (unknown origin) at upto 10 uM | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 6. | ALA5116778 | B | Inhibition of G9a (unknown origin) assessed as effect on H3K9 methylation by cell based assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA5116780 | F | Induction of skeletal muscle differentiation in mouse C2C12 cells assessed as formation of myosin heavy chain positive myotubes at 5 to 250 nM incubated for 48 hrs in growth medium followed by incubation without compounds by immunofluorescence analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5116781 | F | Induction of skeletal muscle differentiation in MuSCs isolated form C57BL/10ScSn-Dme mdx/J mouse assessed as formation of larger myotubes with increased fusion index at 5 to 25 nM incubated for 48 hrs in growth medium followed by incubation without compounds by immunofluorescence analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5116782 | F | Anti-fibroadipogenic activity in FAPs cells isolated from C57BL/10ScSn-Dme mdx/J mouse assessed as impaired adipogenic differentiation at 5 to 25 nM incubated for 48 hrs in growth medium followed by incubation without compounds by immunofluorescence analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5116783 | A | Metabolic stability in mouse hepatocytes assessed as intrinsic clearance measured per million cells | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5116784 | A | Metabolic stability in human hepatocytes assessed as intrinsic clearance measured per million cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5116785 | A | Metabolic stability in mouse hepatocytes assessed as half life | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5116786 | A | Metabolic stability in human hepatocytes assessed as half life | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5116787 | A | Cmax in mouse at 2 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5116788 | A | AUC (0 to 24 hrs) in mouse at 2 mg/kg, ip | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5116789 | A | Inhibition of CYP3A4 (unknown origin) at up to 30 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5116790 | A | Inhibition of CYP1A2 (unknown origin) at up to 30 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA5116791 | A | Inhibition of CYP2D6 (unknown origin) at up to 30 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5116792 | T | Inhibition of hERG at up to 30 uM | Homo sapiens | 1 | assay format | Scientific Literature |
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