# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5108594 | B | Non competitive type inhibition of human TS assessed as inhibition constant using varying levels of mTHF as substrate by UV-Vis spectroscopy based analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
2. | ALA5108595 | B | Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP as substrate by UV-Vis spectroscopy based analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
3. | ALA5108602 | F | Cytotoxicity against human IGROV-1 cells assessed as growth inhibition at 0.1 to 2.5 uM measured upto 72 hrs by crystal violet dye assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA5108603 | F | Cytotoxicity against human TOV112D cells assessed as growth inhibition at 0.1 to 2.5 uM measured upto 72 hrs by crystal violet dye assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA5108606 | B | Displacement of [3H]FA from FRalpha in human IGROV-1 cell surface at 5 uM by flow cytometric analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA5108607 | F | Reduction of hTS expression in human IGROV-1 cells at 5 uM measured after 48 hrs by immunoblot quantitative analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5108609 | F | Reduction of HSP90-alpha expression in human IGROV-1 cells at 5 uM measured after 48 hrs by immunoblot quantitative analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA5108610 | B | Reduction in intracellular TS activity in human IGROV-1 cells measured at 1.25 uM by tritium release assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5108611 | B | Reduction in intracellular TS activity in human IGROV-1 cells measured at 2.5 uM by tritium release assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA5108612 | B | Reduction in intracellular TS activity in human IGROV-1 cells assessed as residual activity measured at 5 uM by tritium release assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature |