# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5135916 | B | Binding affinity to wild type JAK2 JH2 pseudokinase domain (unknown origin) expressed in Sf9 cells and measured upto 30 mins by competitive fluorescence polarization assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
2. | ALA5135918 | B | Binding affinity to wild type JAK2 JH2 pseudokinase domain (unknown origin) V617F mutant expressed in Sf9 cells and measured upto 30 mins by competitive fluorescence polarization assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA5135919 | B | Binding affinity to wild type JAK2 JH1 catalytic domain (unknown origin) expressed in Sf9 cells and measured upto 30 mins by competitive fluorescence polarization assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA5135920 | B | Selectivity index, ratio of Kd for Binding affinity to wild type JAK2 JH1 catalytic domain (unknown origin) expressed in Sf9 cells to Binding affinity to wild type JAK2 JH2 pseudokinase domain (unknown origin) expressed in Sf9 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA5135921 | B | Binding affinity to JAK2 JH2 pseudokinase domainV617F mutant in human HEL 92.1.7 assessed as inhibition of STAT5 phosphorylation at 75 uM for 3 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA5135924 | A | Permeability of compound in PBS buffer at pH 7.4 at 500 mM incubated for 18 hrs by UV plate reader based PAMPA assay | 3 | assay format | Scientific Literature |