| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5164516 | F | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by Fluo-4AM staining based fluorescence assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
| 2. | ALA5164517 | F | Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by by Fluo-4AM staining based fluorescence assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 3. | ALA5164526 | B | Selectivity index, ratio of IC50 for human muscarinic M1 receptor expressed in CHO cells to IC50 for human muscarinic M5 receptor expressed in CHO cells | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 4. | ALA5164527 | F | Antagonist activity at human muscarinic M5 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by by Fluo-4AM staining based fluorescence assay relative to control | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 5. | ALA5164528 | F | Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by by Fluo-4AM staining based fluorescence assay relative to control | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 6. | ALA5164529 | A | Brain to plasma concentration ratio in Sprague-Dawley rat at 0.2 mg/kg, iv administered as cassette dose | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
| 7. | ALA5164530 | A | Unbound brain-to-plasma concentration ratio in Sprague-Dawley rat at 0.2 mg/kg, iv administered as cassette dose | Rattus norvegicus | 9 | organism-based format | Scientific Literature |
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