# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5152254 | B | Inhibition of full length human recombinant Endoplasmic reticulum alpha-glucosidase 1 expressed in Escherichia coli using trisaccharide as substrate incubated for 60 mins | Homo sapiens | 11 | ALA5150012 | assay format | Scientific Literature | |
2. | ALA5152255 | B | Inhibition of full length N-terminal his6-tagged mouse recombinant Endoplasmic reticulum alpha-glucosidase 2 expressed in DH10 Escherichia coli using Fluorogenic 1,4-methyl-lumbelliferon as substrate preincubated for 60 mins followed by substrate addition and measured after 30 mins | Mus musculus | 11 | ALA5150012 | assay format | Scientific Literature | |
3. | ALA5152256 | T | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 3 to 5 days by Cell titer-glo luminescent assay | Chlorocebus sabaeus | 12 | ALA5150012 | cell-based format | Scientific Literature | |
4. | ALA5152257 | F | Antiviral activity against DENV New Guinea C strain infected in African green monkey Vero cells assessed as reduction in viral infection measured after 5 days by plaque assay | dengue virus type 1 | 12 | ALA5150012 | organism-based format | Scientific Literature | |
5. | ALA5152258 | F | Antiviral activity against SARS-CoV-2 England/2/2022 assessed as reduction in viral infection | Severe acute respiratory syndrome coronavirus 2 | 12 | ALA5150012 | organism-based format | Scientific Literature | |
6. | ALA5152259 | T | Selectivity index, ratio of CC50 for cytotoxicity against African green monkey Vero cells to IC50 for antiviral activity against DENV New Guinea C strain infected in African green monkey Vero cells | 3 | ALA5150012 | cell-based format | Scientific Literature |