| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5133738 | B | Inhibition of His-tagged recombinant human ABL1 at 1 uM | Homo sapiens | 1 | ALA5131443 | single protein format | Scientific Literature | |
| 2. | ALA5133739 | F | Induction of apoptosis in human MOLM-13 cells assessed as increase number of apoptotic cells at 10 to 50 nM measured after 72 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 3. | ALA5133740 | B | Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system by LanthaScreen assay | Homo sapiens | 2 | ALA5131443 | assay format | Scientific Literature | |
| 4. | ALA5133741 | B | Inhibition of recombinant N-terminal GST/His6-tagged human FLT3 ITD mutant (571 to 993 residues) expressed in insect cells by LanthaScreen assay | Homo sapiens | 2 | ALA5131443 | cell-based format | Scientific Literature | |
| 5. | ALA5133742 | B | Inhibition of recombinant His-tagged human FLT3 D835Y mutant (564 to 958 residues) expressed in baculovirus expression system by LanthaScreen assay | Homo sapiens | 2 | ALA5131443 | assay format | Scientific Literature | |
| 6. | ALA5133743 | B | Inhibition of recombinant His-tagged human TrKA expressed in baculovirus expression system by LanthaScreen assay | Homo sapiens | 2 | ALA5131443 | assay format | Scientific Literature | |
| 7. | ALA5133744 | F | Anticancer activity against human MOLM-13 cells expressing heterogenous AML-FLT3-ITD assessed as cell viability after 72 hrs by ATP Cell Titer G1oTM assay | Homo sapiens | 3 | ALA5131443 | cell-based format | Scientific Literature | |
| 8. | ALA5133745 | F | Anticancer activity against human MV4-11 cells expressing homozygous AML-FLT3-ITD assessed as cell viability after 72 hrs by ATP Cell Titer G1oTM assay | Homo sapiens | 3 | ALA5131443 | cell-based format | Scientific Literature | |
| 9. | ALA5133746 | F | Inhibition of colony formation in human MV4-11 cells at 500 nM measured after 14 days | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 10. | ALA5133747 | F | Inhibition of colony formation in human MOLM-13 cells at 500 nM measured after 7 days | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 11. | ALA5133748 | F | Anticancer activity against human GDM-1 cells assessed as cell viability after 72 hrs by ATP Cell Titer G1oTM assay | Homo sapiens | 2 | ALA5131443 | cell-based format | Scientific Literature | |
| 12. | ALA5133749 | F | Anticancer activity against human THP-1 cells assessed as cell viability after 72 hrs by ATP Cell Titer G1oTM assay | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 13. | ALA5133750 | F | Anticancer activity against human U-251 cells assessed as cell viability after 72 hrs by ATP Cell Titer G1oTM assay | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 14. | ALA5133751 | F | Anticancer activity against human CAKI-1 cells assessed as cell viability after 72 hrs by ATP Cell Titer G1oTM assay | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 15. | ALA5133752 | F | Anticancer activity against human KM12 cells assessed as cell viability after 72 hrs by ATP Cell Titer G1oTM assay | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 16. | ALA5133753 | B | Inhibition of FLT3-ITD mutant in human MOLM-13 cells assessed as decrease in Erk1/2 phosphorylation measured after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 17. | ALA5133754 | B | Inhibition of FLT3-ITD mutant in human MOLM-13 cells assessed as decrease in p-S6 kinase level measured after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 18. | ALA5133755 | B | Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as decrease in p-S6 kinase level measured after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 19. | ALA5133756 | B | Inhibition of FLT3-ITD mutant in human MV4-11 cells assessed as decrease in Erk1/2 phosphorylation measured after 24 to 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature | |
| 20. | ALA5133757 | F | Cell cycle arrest in human MOLM-13 cells assessed as accumulation at G0/G1 phase at 10 to 50 nM measured after 72 hrs by flow cytometry | Homo sapiens | 1 | ALA5131443 | cell-based format | Scientific Literature |
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