# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5162234 | F | Activation of IRF-mediated immune response in human THP1-Dual KO-STING cells co-expressing ISRE reporter assessed as normalized luciferase gene expression by measuring relative luciferase units at 50 uM incubated for 24 hrs by QUANTI Luc based microplate reader method | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
2. | ALA5162235 | B | Induction of STING dependent immune response in human wild type THP1-Dual cells co-expressing ISRE reporter assessed as normalized luciferase gene expression by measuring relative luciferase units at 50 uM incubated for 24 hrs by QUANTI Luc based microplate reader method | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
3. | ALA5162239 | B | Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hrs by QUANTI Luc based microplate reader method | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
4. | ALA5162240 | F | Cytotoxicity against human wild type THP1-Dual cells assessed as residual cell viability by CellTiter96 Aqueous One Solution Cell Proliferation Assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
5. | ALA5162241 | F | Cytotoxicity against human THP1-Dual KO-STING cells assessed as residual cell viability by CellTiter96 Aqueous One Solution Cell Proliferation Assay | Homo sapiens | 39 | cell-based format | Scientific Literature |